dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016633
Uniprot Accession Q12373; HIF1_YEAST; D6VXY2;
Genbank Protein ID NP_013078.1;
Genbank Nucleotide ID NM_001181842.1;
Protein Name HAT1-interacting factor 1
Protein Synonyms/Alias
Gene Name HIF1
Gene Synonyms/Alias YLL022C;L1205;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Histone H3 and H4 specific chaperone component of the nuclear histone acetyltransferase B (HAT-B) complex. Involved in chromatin assembly and telomere silencing.
Phosphorylation Sites
 dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
141DLTGDVDSGDSEDSGPHOSIDA;curated21081558; 22817900; 19795423
144GDVDSGDSEDSGEGSPHOSIDA;curated21081558; 22817900; 19795423
147DSGDSEDSGEGSEEEPHOSIDA;curated21081558; 22817900; 19795423
151SEDSGEGSEEEEENVPHOSIDA;curated21081558; 22817900; 19795423
174LHELANFSPANEHDDdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19779198; 19366988; 26040406;
353HGSKRPLSQPTTSIGcurated22817900; 24961812; 20377248
356KRPLSQPTTSIGFPAcurated22817900; 20377248
375LGDFNDLSQLVKKKPcurated24961812
Sequence
(Fasta)		MKLRAEDVLA NGTSRHKVQI DMERQVQIAK DLLAQKKFLE AAKRCQQTLD SLPKDGLLPD 60
PELFTIFAQA VYNMEVQNSG NLFGDALLAG DDGSGSESES EPESDVSNGE EGNENGQTEI 120
PNSRMFQFDQ EEEDLTGDVD SGDSEDSGEG SEEEEENVEK EEERLALHEL ANFSPANEHD 180
DEIEDVSQLR KSGFHIYFEN DLYENALDLL AQALMLLGRP TADGQSLTEN SRLRIGDVYI 240
LMGDIEREAE MFSRAIHHYL KALGYYKTLK PAEQVTEKVI QAEFLVCDAL RWVDQVPAKD 300
KLKRFKHAKA LLEKHMTTRP KDSELQQARL AQIQDDIDEV QENQQHGSKR PLSQPTTSIG 360
FPALEKPLGD FNDLSQLVKK KPRRH 386
Keyword

KW-0002--3D-structure
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR011990--TPR-like_helical_dom
PROSITE
Pfam
Gene Ontology

GO:0000123--C:histone acetyltransferase complex
GO:0005634--C:nucleus
GO:0042393--F:histone binding
GO:0006348--P:chromatin silencing at telomere
GO:0016573--P:histone acetylation
GO:0006334--P:nucleosome assembly
GO:0006351--P:transcription, DNA-templated