dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016630
Uniprot Accession Q12366; NDJ1_YEAST; D6W1W2;
Genbank Protein ID NP_014537.1;
Genbank Nucleotide ID NM_001183358.1;
Protein Name Non-disjunction protein 1
Protein Synonyms/Alias Telomere-associated meiosis protein 1;
Gene Name NDJ1
Gene Synonyms/Alias TAM1;YOL104C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Required for telomeric clustering (bouquet stage) during meiosis 1 prophase, formation and efficient homolog pairing, meiosis 1 disjunction, and telomere deletion during meiosis. Promotes also meiotic recombination.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
74LNQVDLVTNLQDSTKdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
Sequence
(Fasta)
MSKDNRLASI LLQPVASSSG NCTEFHDSKL HTLQEELNFL PLEGVASNVC PPMFRGHKNY 60
VFVLYCLNQV DLVTNLQDST KRYYPLQIFK DCQLSSLVQK DFSHYFQLSR QKEGEDRNDS 120
DTTLVNVVNS GVSRHRSQLL KMCIIPRICS FDKSNSKTYK LIQEYVNRFE TVLTKFGPEK 180
DFTKVYANWS KLIESFNELI LHDLLVKWQQ WSELTQPNAT VHQNIPNVLR ELVIKLTQRY 240
FTFQPSYSCS IDEFTTILLN KNALSLLDVF RKPRKYKLNF GLWLDCQNGI LIFTNGIVQM 300
ADEITSERVK SFVRPAHLLV LEDHSNDEAV KKLMFFTFSA ILQCFTDEIL NC 353
Keyword

KW-0158--Chromosome
KW-0181--Complete proteome
KW-0469--Meiosis
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0779--Telomere

Interpro
PROSITE
Pfam
Gene Ontology

GO:0035974--C:meiotic spindle pole body
GO:0000784--C:nuclear chromosome, telomeric region
GO:0042162--F:telomeric DNA binding
GO:0070197--P:meiotic attachment of telomere to nuclear envelope
GO:0045141--P:meiotic telomere clustering
GO:2000711--P:positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric
GO:0007131--P:reciprocal meiotic recombination
GO:0010520--P:regulation of reciprocal meiotic recombination
GO:0007129--P:synapsis