dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016629
Uniprot Accession Q12365; BBP1_YEAST; D6W3B6;
Genbank Protein ID NP_015068.1;
Genbank Nucleotide ID NM_001184069.1;
Protein Name Spindle pole component BBP1
Protein Synonyms/Alias BFR1-binding protein 1;
Gene Name BBP1
Gene Synonyms/Alias YPL255W;P0745;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication. Connects the central plaque of the SPB with the half-bridge. Required for proper localization of CDC5 at the SPB and for proper M-phase progression.
Phosphorylation Sites
 dbPAF PTMs: 23 (View all)
PositionPeptidesSourceReferences ( PMIDs )
7-MNQEDNTGGGGIFGPhosphoGRID 2.0;curated19823750; 19795423; 26040289; 22817900; 23607784
19IFGLFKWTKDALFGTcurated22817900
26TKDALFGTDISPSMKPhosphoGRID 2.021126336
29ALFGTDISPSMKYKDPhosphoGRID 2.0;PHOSIDA;UniProt;curated20702584; 19823750; 19779198; 19795423; 21081558; 26040289;
31FGTDISPSMKYKDQEcurated22817900; 19823750
51SRYAQDDTNFSMKFGcurated25704821
54AQDDTNFSMKFGNDScurated25704821; 25315811
65GNDSNRRSTNLSRSNPhosphoPep 2.019060867
66NDSNRRSTNLSRSNScurated22817900
69NRRSTNLSRSNSWSGPhosphoPep 2.0;curated19060867; 22817900
71RSTNLSRSNSWSGLDdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 21081558; 19060867; 19366988;
73TNLSRSNSWSGLDSTdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated15665377; 18407956; 16381945; 23193290; 17330950; 20702584;
75LSRSNSWSGLDSTLHPhosphoGRID 2.0;PHOSIDA;curated21177495; 21081558; 22817900; 19795423
112HSKERIRSLRSPAPIPhosphoGRID 2.0;curated19779198; 22817900
115ERIRSLRSPAPIVPRdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 16381945; 23193290; 19779198; 19060867; 19366988;
179GVNEVRRSPYKLSVKcurated25521595
181NEVRRSPYKLSVKDIPhosphoPep 2.019060867
194DIPGKFPSPLTKRDEcurated25521595; 25315811
197GKFPSPLTKRDEIDNcurated25521595
333QTLKQRLSDLELKYTcurated22817900
Sequence
(Fasta)		MNQEDNTGGG GIFGLFKWTK DALFGTDISP SMKYKDQEER RDRSRYAQDD TNFSMKFGND 60
SNRRSTNLSR SNSWSGLDST LHRKYELLPE YNENGFNSIV NGDHHSKERI RSLRSPAPIV 120
PREPLRNEPT DTFGHRLHTK RRTINELSNS QIPFIPPQED DPLLSKLFNK DGVNEVRRSP 180
YKLSVKDIPG KFPSPLTKRD EIDNYYVRDE DACHKNREYK KAYFDLFAQM DLNSRDLEDL 240
CEDVREQREQ FHRNEQTYKQ AYEEMRAELV NELKKSKTLF ENYYSLGQKY KSLKKVLDQT 300
ISHEAELATS RERLYQEEDL KNFEIQTLKQ RLSDLELKYT NLQIEKDMQR DNYESEIHDL 360
LLQLSLRNNE RKDTSAGSNI FSTGQ 386
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR029330--Bbp1_C
IPR029328--Bbp1_N
PROSITE
Pfam

PF15272--BBP1_C
PF15271--BBP1_N
Gene Ontology

GO:0005823--C:central plaque of spindle pole body
GO:0005198--F:structural molecule activity
GO:0071988--P:protein localization to spindle pole body
GO:0030474--P:spindle pole body duplication