dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016624
Uniprot Accession Q12358; JLP1_YEAST; D6VXV1;
Genbank Protein ID NP_013043.1;
Genbank Nucleotide ID NM_001181877.1;
Protein Name Alpha-ketoglutarate-dependent sulfonate dioxygenase
Protein Synonyms/Alias
Gene Name JLP1
Gene Synonyms/Alias YLL057C;L0572;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Acts as a alpha-ketoglutarate-dependent dioxygenase active on sulfonates. Although taurine is a poor substrate, a variety of other sulfonates are utilized, with the best natural substrates being isethionate and taurocholate.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
52YDGQDEVSPSGLLKIPhosphoGRID 2.0;UniProt;curated19779198; 22817900
Sequence
(Fasta)
MSPAAAQTAI PLPSTDLPVK IITNGLKNLN YTSKQGYGNF DTHFYDGQDE VSPSGLLKIR 60
KSYREKSKYP DYLPTWDPTE KYGPLEFHEY HDPALRADGN FSNLFAKENV GQLKVKKITP 120
KLGLEINGIQ LTDLSDAAKD ELALLVAQKG VVVFRNQNFA DEGPDYVTEY GRHFGKLHIH 180
QTSGHPQNNP ELHITFRRPD AEEFARVFDD STSSGGWHTD VSYELQPPSY TFFSVVEGPD 240
GGGDTLFADT IEAFDRLSKP LQDFLSTLHV IHSSKEQAEN SQRQGGIKRR APVTHIHPLV 300
RVHPVLKKKC LYVNRAFSRK IVELKRQESE SLLNFLYNLV ESSHDLQLRA KWEPHSVVIW 360
DNRRVQHSAV IDWEEPIHRH AFRITPQAER PVEDLKFLND ENYYPSSLTL DI 413
Keyword

KW-0181--Complete proteome
KW-0223--Dioxygenase
KW-0408--Iron
KW-0479--Metal-binding
KW-0560--Oxidoreductase
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR003819--TauD/TfdA-like

PROSITE
Pfam

PF02668--TauD

Gene Ontology

GO:0046872--F:metal ion binding
GO:0000907--F:sulfonate dioxygenase activity
GO:0046306--P:alkanesulfonate catabolic process
GO:0044273--P:sulfur compound catabolic process