dbPAF Protein Information
| Tag | Content | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0016621 | ||||||||||||
| Uniprot Accession | Q12348; CSN10_YEAST; D6W1V0; | ||||||||||||
| Genbank Protein ID | NP_014524.1; | ||||||||||||
| Genbank Nucleotide ID | NM_001183371.1; | ||||||||||||
| Protein Name | COP9 signalosome complex subunit 10 | ||||||||||||
| Protein Synonyms/Alias | |||||||||||||
| Gene Name | RRI2 | ||||||||||||
| Gene Synonyms/Alias | CSN10;YOL117W; | ||||||||||||
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) | ||||||||||||
| NCBI Taxa ID | 559292 | ||||||||||||
| Functional Description (View all) |
Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes. The CSN complex is involved in the regulation of the mating pheromone response. | ||||||||||||
| Phosphorylation Sites |
dbPAF PTMs: 2
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| Sequence (Fasta) | MSDEDNNYDD FMLSDDEGME SIEMEEETDD EDKQNIEINE DNSQDDQDRG AARHKQHEQG 60 TFEKHDRVED ICERIFEQGQ ALKEDERYKE ARDLFLKIYY KEEFSSDESI ERLMTWKFKS 120 LIEILRLRAL QLYFQKNGAQ DLVLQILEDT ATMSVFLQRI DFQIDGNIFE LLSDTFEVLA 180 PKWERVFLFD IEKVDRENMI CKIDFQKNFM DQFQWILRKP GKDCKLQNLQ RIIRKKIFIA 240 VVWYQRLTMG NVFTPEISSQ IEILVKDNEC SSFEENNDLE SVSMLLQYYI LEYMNTARIN 300 NRRLFKKCID FFEMLISKSL TFSQESGLMV ILYTSKIVFI LDSDSENDLS FALMRYYDRK 360 EELKNMFLYI LKHLEEMGKL RERDITSLFH KFILSGFIFT SMILEAISTD KINPFGFEQV 420 KIALGSPIVN VLEDVYRCFA QLELRQLNAS ISLIPELSVV LSGIIQDIYY LAQTLKLWRK 480 IARLYSCISI SDIISMLQIS DDNEMTRDDL LTILMRSIMK NRSVVYFKLD LTSDLVYFGD 540 ENKVMLPRCS KEEFRLMISP KDEETTEKAR LIDFEYVNDV AIYNNPTRIR TKSSKEFFNT 600 LRKSRETVKL PRVSNQSNED TFLPSYMKFS NKYLELCKLA SNNLE 646 |
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| Keyword | KW-0181--Complete proteome |
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| Interpro | |||||||||||||
| PROSITE | |||||||||||||
| Pfam | |||||||||||||
| Gene Ontology | GO:0008180--C:COP9 signalosome |