dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016615
Uniprot Accession Q12340; YRM1_YEAST; D6W2M8; E9PAH0; Q6B2M3;
Genbank Protein ID NP_014815.3;
Genbank Nucleotide ID NM_001183591.3;
Protein Name Zinc finger transcription factor YRM1
Protein Synonyms/Alias Reveromycin resistance modulator 1;
Gene Name YRM1
Gene Synonyms/Alias YOR172W;O3620;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Transcription factor involved in the regulation of multidrug resistance genes. Acts in concert with YRR1.
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
6--MSKRGSLQDRASPcurated25315811
12GSLQDRASPSEETVKcurated26040406; 24961812; 25315811
77ETKELFGSTPNIELLdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
Sequence
(Fasta)
MSKRGSLQDR ASPSEETVKK AQKRRKPIKS CAFCRKRKLR CDQQKPMCST CKTRGRSGCL 60
YTEKFTHKIE TKELFGSTPN IELLKRIEDL EKRLDDKELT EKDVALSTSP FRNPYANFYY 120
LQCKGSGRRI VYGPTSLRTH LSNDDNRFVN TYNQLWSKVK IERNRWKARH KWTMKPETQL 180
LEGPPLEKTG SDILQQVCNV LPSFEQSSKI ITDFFNTELE TNEVSEVLDK TKIINDFTSS 240
FLPSDELLPN GERRIEKLLP STKKNYYKIG VILMILCIRH FYKNTPEEIE KFLIMLTGLS 300
TAKVYFIERA QFLLLKYYHR ELIWACGDDS HMISLVDLLC STAIMLGLHL NIREIYKNQE 360
NIVGSMESLE NLWVWIILSD FNVSLNIGRC LAINSSYFQV DECENGERLP KNTNNYSSTV 420
FFDQSNSCMG KLKRFLRLAR PMLDQIYDRS AFPDLAENCK KLRNFVETEF HPISYYTDSE 480
LISKVPLCEI KVLAQVLNLL LTFYSLRYLI YKEKSVVLEN NILQTILVSF SLVINTTILC 540
FNLDEKHFPE FFDHNCVHLP PFMALSLVYT NFLFPRASTG FCAFLYHKLT LFEKGYYLSS 600
NIKDQEVTDW DLSTLNIPLD KAMNLLTAFK IHSDIFAKWS NDNNKQLRII MARSYTFVIN 660
IALESIYRAV LEKVIKYRTE VENTWLQQLQ DELNGSYSLT DNVNTPIDPS LSDLGVTSAS 720
PLAGNSPGLP PEEVRNNSEN ASHNNETGPI ETELAQTISN EFWTAYNLGW EELMSQPDYK 780
YLFDTQ 787
Keyword

KW-0010--Activator
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc

Interpro

IPR001138--Zn2-C6_fun-type_DNA-bd

PROSITE

PS00463--ZN2_CY6_FUNGAL_1
PS50048--ZN2_CY6_FUNGAL_2

Pfam

PF00172--Zn_clus

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0000981--F:RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated