dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016611
Uniprot Accession Q12333; FRE7_YEAST; D6W1R8;
Genbank Protein ID NP_014489.2;
Genbank Nucleotide ID NM_001183406.1;
Protein Name Ferric/cupric reductase transmembrane component 7
Protein Synonyms/Alias Ferric-chelate reductase 7;
Gene Name FRE7
Gene Synonyms/Alias YOL152W;AOB629;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Cell surface metalloreductase. May be involved in copper homeostasis.
Phosphorylation Sites
 dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
367TIDKGIISNHPFSIFdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
517TFPQTIDTASDQSDLcurated22817900; 20377248
519PQTIDTASDQSDLAKcurated22817900; 20377248
522IDTASDQSDLAKREKcurated22817900; 20377248
540FGQDDTESNSTFDKScurated25315811
542QDDTESNSTFDKSNNcurated25315811
543DDTESNSTFDKSNNEcurated25315811
Sequence
(Fasta)		MIEERDLVLS NGIHCIADIH SELYARLKKE SQAATPWVYQ KQYGKFVTYF VAVIIFLSLI 60
KKLAFMYYDS SEEFLPEKKN SPTTPSVFLA RIMTKLVAFN RYICYRKFPT LIFSYLGIPT 120
SVGTFLVVMA TTLYTLLYCF VPHPFYRPCA GFGSPPLSVR AGIMAISLVP FVFSLSGKIN 180
VIGWLVGLSY EKINIYHQWA SILCLFFSWV HVIPFLRQAR HEGGYERMHQ RWKASDMWRS 240
GVPPILFLNL LWLSSLPIAR RHFYEIFLQL HWILAVGFYI SLFYHVYPEL NSHMYLVATI 300
VVWFAQLFYR LAVKGYLRPG RSFMASTIAN VSIVGEGCVE LIVKDVEMAY SPGQHIFVRT 360
IDKGIISNHP FSIFPSAKYP GGIKMLIRAQ KGFSKRLYES NDDMKKILID GPYGGIERDI 420
RSFTNVYLIC SGSGISTCLP FLQKYGPILH KTNLEVITLD WVVRHREDIS WIRDEMCTLS 480
NNLRQLFLDG KIVVRIYVCS DSTVPGIIKT FPQTIDTASD QSDLAKREKD TEFGQDDTES 540
NSTFDKSNNE YKGLITIIPS KPDLNQVIND YQIGFRNCFI CSGSDSLRYT VGNSVAGLQA 600
KVFSNKNVEE CYLHSESFGY 621
Keyword

KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0186--Copper
KW-0187--Copper transport
KW-0249--Electron transport
KW-0274--FAD
KW-0285--Flavoprotein
KW-0406--Ion transport
KW-0408--Iron
KW-0410--Iron transport
KW-0472--Membrane
KW-0479--Metal-binding
KW-0521--NADP
KW-0560--Oxidoreductase
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
Interpro

IPR013112--FAD-bd_8
IPR017927--Fd_Rdtase_FAD-bd
IPR013130--Fe3_Rdtase_TM_dom
IPR013121--Fe_red_NAD-bd_6
IPR030155--FRE7
IPR017938--Riboflavin_synthase-like_b-brl
PROSITE

PS51384--FAD_FR
Pfam

PF08022--FAD_binding_8
PF01794--Ferric_reduct
PF08030--NAD_binding_6
Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0052851--F:ferric-chelate reductase (NADPH) activity
GO:0000293--F:ferric-chelate reductase activity
GO:0046872--F:metal ion binding
GO:0015677--P:copper ion import
GO:0055072--P:iron ion homeostasis
GO:0006826--P:iron ion transport