dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016605
Uniprot Accession Q12318; PSY3_YEAST; D6VZ12;
Genbank Protein ID NP_013480.1;
Genbank Nucleotide ID NM_001182265.1;
Protein Name Platinum sensitivity protein 3
Protein Synonyms/Alias
Gene Name PSY3
Gene Synonyms/Alias YLR376C;L8039.17;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Required for resistance to the DNA-damaging agents methyl methanesulfonate (MMS), cisplatin and oxaliplatin, but not to mitomycin C. Plays a role in protection against mutation accumulation. May be a component of the recombination-repair pathway.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
202KWSIKRKSGVTLYPTPhosphoGRID 2.020489023
Sequence
(Fasta)
MEVLKNIRIY PLSNFITSTK NYINLPNELR NLISEEQESK LGFLHIIESD FKPSVALQKL 60
VNCTTGDEKI LIIDIVSIWS QQKQRQHGAI YMNSLSCINI TGLIVFLELL YDSPMDALRR 120
CQVDNFNFQL RGIVIDNLSF LNFESDKNYD VINLSKFEKL FKILRKLREF LGCWIITKSF 180
PTDFYNGIEN TLVDKWSIKR KSGVTLYPTK LPDSYMKGMD LIIYREVVDG RPQYRRIAAL 240
EE 243
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0539--Nucleus
KW-1185--Reference proteome

Interpro

IPR031779--Psy3

PROSITE
Pfam

PF16836--PSY3

Gene Ontology

GO:0005634--C:nucleus
GO:0033063--C:Rad51B-Rad51C-Rad51D-XRCC2 complex
GO:0005657--C:replication fork
GO:0097196--C:Shu complex
GO:0035861--C:site of double-strand break
GO:0008094--F:DNA-dependent ATPase activity
GO:0003690--F:double-stranded DNA binding
GO:0000400--F:four-way junction DNA binding
GO:0000150--F:recombinase activity
GO:0003697--F:single-stranded DNA binding
GO:0000730--P:DNA recombinase assembly
GO:0070987--P:error-free translesion synthesis
GO:0000707--P:meiotic DNA recombinase assembly
GO:0006312--P:mitotic recombination
GO:0007131--P:reciprocal meiotic recombination
GO:0000725--P:recombinational repair
GO:0010212--P:response to ionizing radiation
GO:0042148--P:strand invasion