dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016601
Uniprot Accession Q12311; NTO1_YEAST; D6W441;
Genbank Protein ID NP_015356.1;
Genbank Nucleotide ID NM_001184128.1;
Protein Name NuA3 HAT complex component NTO1
Protein Synonyms/Alias
Gene Name NTO1
Gene Synonyms/Alias YPR031W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Component of the NuA3 histone acetyltransferase complex, that acetylates Lys-14 of histone H3. Recruitment of NuA3 to nucleosomes requires methylated histone H3. In conjunction with the FACT complex, NuA3 may be involved in transcriptional regulation.
Phosphorylation Sites
 dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
45VETKDNSTDTDSDDIcurated20377248
47TKDNSTDTDSDDISNcurated22817900; 24961812; 25315811; 20377248
49DNSTDTDSDDISNRNcurated22817900; 25315811; 20377248
115YCVRFNESFISRYYHdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
576LYRLKELTTLVKKRTcurated22817900
588KRTQASNSLSRSRKKPhosphoGRID 2.019779198
590TQASNSLSRSRKKVFPhosphoGRID 2.019779198
592ASNSLSRSRKKVFDIPhosphoGRID 2.019779198
728IMEEEGLSDAEELSAPhosphoGRID 2.0;UniProt;curated19779198; 22817900
Sequence
(Fasta)		MNRGSLDDGP KLREEKHFQD FYPDLNADTL LPFIVPLVET KDNSTDTDSD DISNRNNREI 60
GSVKSVQTKE LIFKGRVTTE PLVLKKNEVE FQKCKITTNE LKGKKNPYCV RFNESFISRY 120
YHINKVRNRK SYKQQQKEFD GVEAPYFTKF SSKEAPNITI STSTKSAIQK FASISPNLVN 180
FKPQYDMDEQ DELYLHYLNK RYFKDQMSHE IFEILMTTLE TEWFHIEKHI PSTNSLIARH 240
NILRDCKNYE LYGSDDGTGL SMDQACAVCL GTDSDNLNTI VFCDGCDIAV HQECYGIIFI 300
PEGKWLCRRC MISKNNFATC LMCPSHTGAF KQTDTGSWVH NICALWLPEL YFSNLHYMEP 360
IEGVQNVSVS RWKLNCYICK KKMGACIQCF QRNCFTAYHV TCARRAGLYM SKGKCTIQEL 420
ASNQFSQKYS VESFCHKHAP RGWQTSIEGI NKARKYFSLL STLQTETPQH NEANDRTNSK 480
FNKTIWKTPN QTPVAPHVFA EILQKVVDFF GLANPPAGAF DICKYWSMKR ELTGGTPLTA 540
CFENNSLGSL TEEQVQTRID FANDQLEDLY RLKELTTLVK KRTQASNSLS RSRKKVFDIV 600
KSPQKYLLKI NVLDIFIKSE QFKALERLVT EPKLLVILEK CKHCDFDTVQ IFKEEIMHFF 660
EVLETLPGAS RILQTVSSKA KEQVTNLIGL IEHVDIKKLL SRDFIINDDK IEERPWSGPV 720
IMEEEGLSDA EELSAGEHRM LKLILNSG 749
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR019542--Enhancer_polycomb-like_N
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF10513--EPL1
Gene Ontology

GO:0005737--C:cytoplasm
GO:0033100--C:NuA3 histone acetyltransferase complex
GO:1990467--C:NuA3a histone acetyltransferase complex
GO:1990468--C:NuA3b histone acetyltransferase complex
GO:0035064--F:methylated histone binding
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated