Tag |
Content |
dbPAF ID |
dbPAF-0016600 |
Uniprot Accession |
Q12310; PRR2_YEAST; D6VRE0; |
Genbank Protein ID |
NP_010067.1; |
Genbank Nucleotide ID |
NM_001180274.1; |
Protein Name |
Serine/threonine-protein kinase PRR2 |
Protein Synonyms/Alias |
Pheromone response regulator 2; |
Gene Name |
PRR2 |
Gene Synonyms/Alias |
YDL214C;D1014; |
Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
NCBI Taxa ID |
559292 |
Functional Description (View all) |
Protein kinase that functions as regulator in the pheromone-induced mating pathway downstream of mitogen-activated protein kinase (MAPK) FUS3. Diminishes transcriptional induction of genes in response to pheromone signaling.Functional Description
Protein kinase that functions as regulator in the pheromone-induced mating pathway downstream of mitogen-activated protein kinase (MAPK) FUS3. Diminishes transcriptional induction of genes in response to pheromone signaling.
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Phosphorylation Sites
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dbPAF PTMs: 7 Position | Peptides | Source | References ( PMIDs ) |
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57 | TGEALNKSYDSVFSS | PhosphoGRID 2.0 | 20489023 | 63 | KSYDSVFSSLPVADS | PhosphoGRID 2.0 | 20489023 | 64 | SYDSVFSSLPVADSV | PhosphoGRID 2.0 | 20489023 | 112 | ENISKIDSNIISSPM | PhosphoGRID 2.0 | 20489023 | 138 | KGRLRKNSTDFTSSF | PhosphoGRID 2.0 | 20489023 | 150 | SSFSNSLSLPKSYGK | PhosphoGRID 2.0 | 20489023 | 231 | MFTTRVYSLEDSVSS | PhosphoGRID 2.0 | 20489023 |
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Sequence (Fasta) | MSLSRILRYN QRNNKTTASL TAEHAYSDNW AYSVSLGDPT SVGVNMAAKT GEALNKSYDS 60 VFSSLPVADS VPRTDFTASS RDDENTDVQK LTTSWMEKID TKMPENISKI DSNIISSPMV 120 SKVEARFIVP KGRLRKNSTD FTSSFSNSLS LPKSYGKLIF FTSKKNSSST KKNLANDISD 180 NKHNNNSSNT IGHNIPVTTA TATCDEIACT STEHEYNVYE EERMFTTRVY SLEDSVSSLS 240 TNPLDDTYSE AVQVNTRHIE DTESTAHIRK HSYTTSLSSI KRLFKITSFS NNNSNSCDHQ 300 ESTVADDCAI SSSLKETTSS PVSTGSFSLM IENEDSDRDQ IIQALYSNIE ASTDLVSRKY 360 RDLDVVLGEG SGGKVKLVQR VLDNKVFALK EYRSKKKRES ERKYIKNIIS EYCIASTLKN 420 PNICETLEIL YEKGKIFQIL EYCEYDLFSL VMSEKMHYEE ICCLFKQLIN GVKYLHDIGL 480 SHRDLKLDNC VVTRRGILKL IDFGASSVFH YPLSSQMIEA NGIVGSDPYL SPEVFYFNEY 540 DPRALDVWSV GIIFFCMITR RFPWKYPKVK DVQFKAFCSG RGVSSFKDLV TRPATDDSNN 600 YDNDGYEEGV IDMGPNFILH RLPEETHKIM RRILEVSPFR RITINGILQD GWIKEIETCQ 660 VVGAASPNEA SLRIINKGNH IHTNIDQRYA HIGGLHQRT
Fasta Sequence
>Q12310|PRR2|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) MSLSRILRYNQRNNKTTASLTAEHAYSDNWAYSVSLGDPTSVGVNMAAKTGEALNKSYDSVFSSLPVADSVPRTDFTASSRDDENTDVQKLTTSWMEKIDTKMPENISKIDSNIISSPMVSKVEARFIVPKGRLRKNSTDFTSSFSNSLSLPKSYGKLIFFTSKKNSSSTKKNLANDISDNKHNNNSSNTIGHNIPVTTATATCDEIACTSTEHEYNVYEEERMFTTRVYSLEDSVSSLSTNPLDDTYSEAVQVNTRHIEDTESTAHIRKHSYTTSLSSIKRLFKITSFSNNNSNSCDHQESTVADDCAISSSLKETTSSPVSTGSFSLMIENEDSDRDQIIQALYSNIEASTDLVSRKYRDLDVVLGEGSGGKVKLVQRVLDNKVFALKEYRSKKKRESERKYIKNIISEYCIASTLKNPNICETLEILYEKGKIFQILEYCEYDLFSLVMSEKMHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITRRFPWKYPKVKDVQFKAFCSGRGVSSFKDLVTRPATDDSNNYDNDGYEEGVIDMGPNFILHRLPEETHKIMRRILEVSPFRRITINGILQDGWIKEIETCQVVGAASPNEASLRIINKGNHIHTNIDQRYAHIGGLHQRT
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Keyword |
KW-0067--ATP-binding KW-0181--Complete proteome KW-0418--Kinase KW-0547--Nucleotide-binding KW-0589--Pheromone response KW-1185--Reference proteome KW-0723--Serine/threonine-protein kinase KW-0808--Transferase
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Interpro |
IPR011009--Kinase-like_dom IPR000719--Prot_kinase_dom IPR017441--Protein_kinase_ATP_BS IPR008271--Ser/Thr_kinase_AS
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PROSITE |
PS00107--PROTEIN_KINASE_ATP PS50011--PROTEIN_KINASE_DOM PS00108--PROTEIN_KINASE_ST
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Pfam |
PF00069--Pkinase
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Gene Ontology |
GO:0005737--C:cytoplasm GO:0005524--F:ATP binding GO:0004674--F:protein serine/threonine kinase activity GO:0035556--P:intracellular signal transduction GO:0031138--P:negative regulation of conjugation with cellular fusion GO:0046020--P:negative regulation of transcription from RNA polymerase II promoter by pheromones
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