dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016595
Uniprot Accession Q12296; MAM3_YEAST; D6W207;
Genbank Protein ID NP_014581.1;
Genbank Nucleotide ID NM_001183315.1;
Protein Name Protein MAM3
Protein Synonyms/Alias
Gene Name MAM3
Gene Synonyms/Alias YOL060C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Involved in metal homeostasis and more specially in manganese sensitivity.
Phosphorylation Sites
 dbPAF PTMs: 48 (View all)
PositionPeptidesSourceReferences ( PMIDs )
45SGSHVLNSRDVADSGdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
237TMGVERLTKDEVTIIcurated22817900
242RLTKDEVTIISAVLDPhosphoGRID 2.0;curated19823750; 19795423; 22817900
245KDEVTIISAVLDLKAPhosphoGRID 2.0;curated19823750; 19795423; 22817900
434AADQADESSPLLSPSPhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;curated19823750; 19795423; 21081558; 19060867; 24961812; 20377248
435ADQADESSPLLSPSNPhosphoPep 2.0;curated19060867; 26040289; 22817900; 24961812; 25315811; 20377248
439DESSPLLSPSNSNHPdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17563356; 18407956; 16381945; 23193290; 19823750; 19779198;
441SSPLLSPSNSNHPSEdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 21081558; 19060867; 19366988;
443PLLSPSNSNHPSEHPPhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;curated19779198; 21081558; 19060867; 26040289; 22369663; 22817900;
447PSNSNHPSEHPQQDLPhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;UniProt;curated19779198; 21081558; 19060867; 26040289; 22369663; 22817900;
463NKSWKQKSNDGYDRScurated25315811
475DRSNAVLSPTPQVTEPhosphoPep 2.0;curated19060867; 23607784
477SNAVLSPTPQVTEHGcurated26040289; 25882841; 20377248
485PQVTEHGTIIPSNLAcurated20377248
501NPLNVNKSFVTIKKPcurated22369663; 22817900
516ANVPKIITTHTPHSSPhosphoPep 2.0;curated19060867; 26040406; 20377248
517NVPKIITTHTPHSSKPhosphoPep 2.0;curated19060867; 26040406; 22817900; 24961812; 20377248
519PKIITTHTPHSSKEPdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated17287358; 16381945; 23193290; 21177495; 19779198; 21081558;
522ITTHTPHSSKEPSPAPhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;curated21177495; 19779198; 21081558; 19060867; 26040406; 22369663;
523TTHTPHSSKEPSPAPdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated17287358; 16381945; 23193290; 21177495; 19779198; 21081558;
Sequence
(Fasta)		MSFLPLRSRS RSGAPHWVYI ILYHIFTIPK IYSLPLLSGS HVLNSRDVAD SGHSVGDEAS 60
VTTYYIISII LVLLGGVFAG LTLGLMGQDE VYLKVISTSG SNSEKKLAKR VLDLISRGKH 120
WVLVTLLLSN VITNETLPIV LDRCLGGGWQ AVVSSTILIV IFGEIIPQSV CVKYGLQVGA 180
FFCPFVLVLM YLMYPVAYPI ATLLDYMLGE DHGTMYKKSG LKTLVTLHRT MGVERLTKDE 240
VTIISAVLDL KAKRVEEIMT PIENVFTMSA DTILDDKTVE KIFNSGFSRI PIFLPNEPNN 300
FIGMLLVRVL ISYDPDDCLP ISHFPLATLP ETSPNTSCLN ILNYFQEGKA HMCVVSKEPG 360
SSHGAIGVLT LEDVIEELIG EEIVDESDVF VDMHQHIMRQ QPGPLSKRHI TSYLHHLYTS 420
SHKEHKAADQ ADESSPLLSP SNSNHPSEHP QQDLNNKSWK QKSNDGYDRS NAVLSPTPQV 480
TEHGTIIPSN LASNPLNVNK SFVTIKKPAN VPKIITTHTP HSSKEPSPAP HSNDKSLSAE 540
EQQLLSDHAE LSRQAVLHTQ RSGQPTQVTT STKTTRNSPD SISIPNSGAN HGNENQNVTI 600
STSYQNTKNG IVESVITVKG VPKTIIGPAK DWDESKSEYG NENINQENSN RSDDRESSSS 660
NASLFSSIKN KFKNENANNN DRSNFTDSLS RTSNYDANGS SSTIKR 707
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0926--Vacuole
Interpro

IPR000644--CBS_dom
IPR002550--DUF21
PROSITE

PS51371--CBS
Pfam

PF01595--DUF21
Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005774--C:vacuolar membrane
GO:0030026--P:cellular manganese ion homeostasis
GO:0007005--P:mitochondrion organization