dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016594
Uniprot Accession Q12292; ATG34_YEAST; D6W1Y5;
Genbank Protein ID NP_014558.1;
Genbank Nucleotide ID NM_001183337.1;
Protein Name Autophagy-related protein 34
Protein Synonyms/Alias
Gene Name ATG34
Gene Synonyms/Alias ATG19-B;YOL083W;O0957;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Cargo-receptor protein involved in the cytoplasm to vacuole transport (Cvt) and in autophagy. Recognizes cargo proteins, such as AMS1 and delivers them to the pre-autophagosomal structure for eventual engulfment by the autophagosome and targeting to the vacuole.
Phosphorylation Sites
 dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
244EKGERLTTPNDPLLHdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
353SPLASFSTGSFQTGSPhosphoGRID 2.019779198
360TGSFQTGSFHTLQDPdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
363FQTGSFHTLQDPTNVdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
Sequence
(Fasta)		MKIAVETTLF DFFVIDQFKK STFSAPNTKV DTIKGCINKF IEQFNVYDEQ HIFWQPPGKS 60
NVRLLSNAND FGQLGNFLHK KIKCNIFIGE EALRKYDLNI CGPYDKFVEN SDPSVKKVVN 120
RDDVMLSRKC LNIISEQLSI LEKSISKAQN QVLQSSEVEG KKCIILPEDK PELIKFFSKF 180
ETSVQLQEVY EGYKVYEKLL QKFGGQKKRM ESFLNENTPM SGAEAIKQIN ISEELKEKGE 240
RLTTPNDPLL HVEVSNEDNS LHFILYNKTN IIIPGNCTFE FSSQISEVFS IKMGPHEIGI 300
KGQKELWFFP SLPTPLSNYT MKVVNQDGET ILVGKCADSN EITLKSPLAS FSTGSFQTGS 360
FHTLQDPTNV FRADALSSPD ESSIMSTPFL GETDEVYNSG STLSRPFTWE EI 413
Keyword

KW-0002--3D-structure
KW-0072--Autophagy
KW-0181--Complete proteome
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
Interpro

IPR024543--Atg19/Atg34_C
PROSITE
Pfam

PF12744--ATG19_autophagy
Gene Ontology

GO:0034045--C:pre-autophagosomal structure membrane
GO:0030674--F:protein binding, bridging
GO:0006461--P:protein complex assembly
GO:0031503--P:protein complex localization
GO:0071211--P:protein targeting to vacuole involved in autophagy