dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016591
Uniprot Accession Q12284; ERV2_YEAST; D6W448;
Genbank Protein ID NP_015362.1;
Genbank Nucleotide ID NM_001184134.1;
Protein Name FAD-linked sulfhydryl oxidase ERV2
Protein Synonyms/Alias
Gene Name ERV2
Gene Synonyms/Alias YPR037C;YP3085.03C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation in the endoplasmic reticulum lumen in parallel to ERO1.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
43PGLIKAKSGIDEVQGPhosphoGRID 2.021126336
Sequence
(Fasta)
MKQIVKRSHA IRIVAALGII GLWMFFSSNE LSIATPGLIK AKSGIDEVQG AAAEKNDARL 60
KEIEKQTIMP LMGDDKVKKE VGRASWKYFH TLLARFPDEP TPEEREKLHT FIGLYAELYP 120
CGECSYHFVK LIEKYPVQTS SRTAAAMWGC HIHNKVNEYL KKDIYDCATI LEDYDCGCSD 180
SDGKRVSLEK EAKQHG 197
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0256--Endoplasmic reticulum
KW-0274--FAD
KW-0285--Flavoprotein
KW-0472--Membrane
KW-0560--Oxidoreductase
KW-1185--Reference proteome
KW-0735--Signal-anchor
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR017905--ERV/ALR_sulphydryl_oxidase

PROSITE

PS51324--ERV_ALR

Pfam

PF04777--Evr1_Alr

Gene Ontology

GO:0030176--C:integral component of endoplasmic reticulum membrane
GO:0003756--F:protein disulfide isomerase activity
GO:0016972--F:thiol oxidase activity
GO:0055114--P:oxidation-reduction process
GO:0006457--P:protein folding