dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016582
Uniprot Accession Q12266; YB11A_YEAST; D6VPZ7;
Genbank Protein ID NP_009550.1;
Genbank Nucleotide ID NM_001180047.1;
Protein Name Transposon Ty1-BL Gag polyprotein
Protein Synonyms/Alias Gag-p49;Transposon Ty1 protein A;TY1A;TYA;p58;
Gene Name TY1A-BL
Gene Synonyms/Alias YBLWTy1-1 GAG;YBL005W-A;YBL004W-B;YBL0324;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).
Phosphorylation Sites
dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
10SQQLSQHSPIFHGSAcurated26040289
56QANSQQPTTPPSSAVPhosphoGRID 2.0;PhosphoPep 2.019779198; 19060867
57ANSQQPTTPPSSAVPPhosphoGRID 2.0;PhosphoPep 2.0;curated18407956; 19779198; 19060867
60QQPTTPPSSAVPENHdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated17330950; 16381945; 23193290; 21177495; 19060867; 19366988;
61QPTTPPSSAVPENHHPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 17330950; 19060867; 22817900
71PENHHHASPQAAQVPdbPTM 3.0;PhosphoPep 2.0;SysPTM 2.017330950; 16381945; 23193290; 19060867; 19366988
409NVSTFNNSPGPDNDLdbPTM 3.017330950; 16381945; 23193290
Sequence
(Fasta)
MESQQLSQHS PIFHGSACAS VTSKEVQTTQ DPLDISASKT EECEKVSTQA NSQQPTTPPS 60
SAVPENHHHA SPQAAQVPLP QNGPYPQQRM MNTQQANISG WPVYGHPSLM PYPPYQMSPM 120
YAPPGAQSQF TQYPQYVGTH LNTPSPESGN SFPDSSSAKS NMTSTNQHVR PPPILTSPND 180
FLNWVKIYIK FLQNSNLGDI IPTATRKAVR QMTDDELTFL CHTFQLFAPS QFLPPWVKDI 240
LSVDYTDIMK ILSKSINKMQ SDTQEVNDIT TLATLHYNGS TPADAFEAEV TNILDRLNNN 300
GIPINNKVAC QFIMRGLSGE YKFLPYARHR CIHMTVADLF SDIHSMYEEQ QESKRNKSTY 360
RRSPSDEKKD SRTYTNTTKP KSITRNSQKP NNSQSRTARA HNVSTFNNSP GPDNDLIRGS 420
TTEPIQLKNT HDLHLRPGTY 441
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1185--Reference proteome
KW-0688--Ribosomal frameshifting
KW-0694--RNA-binding
KW-0814--Transposable element

Interpro

IPR015820--Retrotransposon_Ty1A_N

PROSITE
Pfam

PF01021--TYA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000943--C:retrotransposon nucleocapsid
GO:0003723--F:RNA binding
GO:0032197--P:transposition, RNA-mediated