dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016580
Uniprot Accession Q12263; GIN4_YEAST; D6VTC9;
Genbank Protein ID NP_010795.3;
Genbank Nucleotide ID NM_001180815.3;
Protein Name Serine/threonine-protein kinase GIN4
Protein Synonyms/Alias Growth inhibitory protein 4;
Gene Name GIN4
Gene Synonyms/Alias YDR507C;D9719.13;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Serine/threonine-protein kinase which regulates the localization and the function of the septins during mitosis. Phosphorylates SHS1.
Phosphorylation Sites
 dbPAF PTMs: 84 (View all)
PositionPeptidesSourceReferences ( PMIDs )
298KYPSIRDSKSIRGLPPhosphoGRID 2.0;curated19779198; 22817900; 25315811
300PSIRDSKSIRGLPREPhosphoGRID 2.0;curated19779198; 22817900
309RGLPREDTYLTPLSEcurated24961812
382QQVKKRQSISSVSVSdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated17287358; 18407956; 16381945; 23193290; 21177495; 20702584;
384VKKRQSISSVSVSPSdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated17287358; 18407956; 16381945; 23193290; 17330950; 21177495;
385KKRQSISSVSVSPSKdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 21177495; 19823750; 19779198;
387RQSISSVSVSPSKKVPhosphoGRID 2.0;curated21177495; 20702584; 26040289; 22817900; 24961812; 20377248
389SISSVSVSPSKKVSTPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 20702584; 19684113; 19823750; 19779198; 19795423;
391SSVSVSPSKKVSTTPdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated17287358; 16381945; 23193290; 19823750; 19795423; 21081558;
395VSPSKKVSTTPQRRRcurated25315811
396SPSKKVSTTPQRRRNPhosphoPep 2.019060867
397PSKKVSTTPQRRRNRdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated17287358; 18407956; 16381945; 23193290; 19060867; 19366988;
406QRRRNRESLISVTSSdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19684113; 19779198; 19060867;
409RNRESLISVTSSRKKdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19684113; 19779198; 19366988;
411RESLISVTSSRKKPIPhosphoGRID 2.0;curated19684113; 26040289; 22817900
412ESLISVTSSRKKPISdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated17287358; 18407956; 16381945; 23193290; 15665377; 21177495;
413SLISVTSSRKKPISFdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated17287358; 18407956; 16381945; 23193290; 20702584; 19779198;
419SSRKKPISFNKFTASPhosphoGRID 2.0;curated19823750; 19795423; 26040289; 22817900
427FNKFTASSASSSNLTcurated22817900
429KFTASSASSSNLTTPdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19060867; 19366988; 26040289;
Sequence
(Fasta)		MAINGNSIPA IKDNTIGPWK LGETLGLGST GKVQLARNGS TGQEAAVKVI SKAVFNTGNV 60
SGTSIVGSTT PDALPYGIER EIIIMKLLNH PNVLRLYDVW ETNTDLYLVL EYAEKGELFN 120
LLVERGPLPE HEAIRFFRQI IIGVSYCHAL GIVHRDLKPE NLLLDHKYNI KIADFGMAAL 180
ETEGKLLETS CGSPHYAAPE IVSGIPYQGF ASDVWSCGVI LFALLTGRLP FDEEDGNIRT 240
LLLKVQKGEF EMPSDDEISR EAQDLIRKIL TVDPERRIKT RDILKHPLLQ KYPSIRDSKS 300
IRGLPREDTY LTPLSESNSS IDATILQNLV ILWHGRDPEG IKEKLREPGA NAEKTLYALL 360
YRFKCDTQKE LIKQQQVKKR QSISSVSVSP SKKVSTTPQR RRNRESLISV TSSRKKPISF 420
NKFTASSASS SNLTTPGSSK RLSKNFSSKK KLSTIVNQSS PTPASRNKRA SVINVEKNQK 480
RASIFSTTKK NKRSSRSIKR MSLIPSMKRE SVTTKLMSTY AKLAEDDDWE YIEKETKRTS 540
SNFATLIDEI FEYEKYEQIR KEKEELERKV REAKAREELE RRRRKQEEKE RARKLLEKED 600
LKRKQEELKK QIEIDISDLE QELSKHKEEK LDGNIRSISA PMENEEKNIN HLEVDIDNIL 660
RRRNFSLQTR PVSRLDPGIM FSSPTEEVSP VEPKRTENER LTTEKKILET IRRSKFLGSS 720
FNIDKELKLS KMEYPSIIAP QRLSEERVVS DSNDGYESLI LPKDGNGVSQ LKDSTATTAP 780
VSDGRLRKIS EIRVPQFTRK SRHFSESNKR LSVLSMYSTK ESFTNLVDIL KNGNLDVNNQ 840
QSQRIPTPRS ADDSEFLFET VNEEAEYTGN SSNDERLYDV GDSTIKDKSA LKLNFADRFN 900
GSNEAKQTDN LHLPILPPLN GDNELRKQNS QEGDQAHPKI KSMIPESGSS SHTEKEEENE 960
EKEEKKPEQH KQEEDQEKRE KVVDDMEPPL NKSVQKIREK NAGSQAKDHS KDHLKEHKQD 1020
KNTAIGNGSF FRKFSKSSDK TMELYAKISA KQLFNGLEKL LRGWTQYGLK NIKSHPNNLT 1080
LTGKLSSDNI FSLRSTLFEV NIYPRGKMSV VQFKKVSGSF KAVKKLVNEV ENVLNKEGVL 1140
QK 1143
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
Interpro

IPR031850--Fungal_KA1_dom
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
Pfam

PF16797--Fungal_KA1
PF00069--Pkinase
Gene Ontology

GO:0005935--C:cellular bud neck
GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004672--F:protein kinase activity
GO:0004674--F:protein serine/threonine kinase activity
GO:0007117--P:budding cell bud growth
GO:0035556--P:intracellular signal transduction
GO:0044879--P:morphogenesis checkpoint
GO:0046777--P:protein autophosphorylation
GO:0006468--P:protein phosphorylation
GO:0000921--P:septin ring assembly