dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016579
Uniprot Accession Q12260; YB21A_YEAST; D6VPQ5;
Genbank Protein ID NP_009451.1;
Genbank Nucleotide ID NM_001180049.1;
Protein Name Transposon Ty2-B Gag polyprotein
Protein Synonyms/Alias
Gene Name TY2A-B
Gene Synonyms/Alias YBLWTy2-1 GAG;YBL100W-A;YBL0821;YBL101W-A;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty2 RNA and initiation of reverse transcription (By similarity).
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
424TVSSQYLSDDNELSLdbPTM 3.017330950; 16381945; 23193290
Sequence
(Fasta)
MESQQLHQNP HSLHGSAYAS VTSKEVSSNQ DPLAVSASNL PEFDRDSTKV NSQQETTPGT 60
SAVPENHHHV SPQPASVPPP QNGQYQQHGM MTPNKAMASN WAHYQQPSMM TCSHYQTSPA 120
YYQPDPHYPL PQYIPPLSTS SPDPIDSQDQ HSEVPQAKTK VRNNVLPPHT LTSEENFYTW 180
VKFYIRFLKN SNLGDIIPND QGEIKRQMTY EEHAYIYNTF QAFAPFHLLP TWVKQILEIN 240
YADILTVLCK SVSKMQTNNQ ELKDWIALAN LEYDGSTSAD TFEITVSTII QRLKENNINV 300
SDRLACQLIL KGLSGDFKYL RNQYRTKTNM KLSQLFAEIQ LIYDENKIMN LNKPSQYKQH 360
SEYKNVSRTS PNTTNTKVTT RNYHRTNSSK PRAAKAHNIA TSSKFSRVNN DHINESTVSS 420
QYLSDDNELS LRPATERI 439
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1185--Reference proteome
KW-0688--Ribosomal frameshifting
KW-0694--RNA-binding
KW-0814--Transposable element

Interpro

IPR015820--Retrotransposon_Ty1A_N

PROSITE
Pfam

PF01021--TYA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000943--C:retrotransposon nucleocapsid
GO:0003723--F:RNA binding
GO:0032197--P:transposition, RNA-mediated