dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0016576 |
| Uniprot Accession | Q12255; NYV1_YEAST; D6VY93; |
| Genbank Protein ID | NP_013194.2; |
| Genbank Nucleotide ID | NM_001181980.1; |
| Protein Name | Vacuolar v-SNARE NYV1 |
| Protein Synonyms/Alias | |
| Gene Name | NYV1 |
| Gene Synonyms/Alias | MAM2;YLR093C; |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID | 559292 |
| Functional Description (View all) |
Vacuolar v-SNARE required for docking. Only involved in homotypic vacuole fusion. Required for Ca(2+) efflux from the vacuolar lumen, a required signal for subsequent membrane fusion events, by inhibiting vacuolar Ca(2+)-ATPase PMC1 and promoting Ca(2+) release when forming trans-SNARE assemblies during the docking step. |
| Phosphorylation Sites |
dbPAF PTMs: 4 |
| Sequence (Fasta) | MKRFNVSYVE VIKNGETISS CFQPFQKNEN YGTITSANEQ ITPVIFHNLI MDMVLPKVVP 60 IKGNKVTKMS MNLIDGFDCF YSTDDHDPKT VYVCFTLVDM PKILPIRILS GLQEYESNAT 120 NELLSSHVGQ ILDSFHEELV EYRNQTLNSS GNGQSSNGNG QNTISDIGDA TEDQIKDVIQ 180 IMNDNIDKFL ERQERVSLLV DKTSQLNSSS NKFRRKAVNI KEIMWWQKVK NITLLTFTII 240 LFVSAAFMFF YLW 254 |
| Keyword | KW-0002--3D-structure |
| Interpro | IPR001388--Synaptobrevin |
| PROSITE | PS50892--V_SNARE |
| Pfam | |
| Gene Ontology | GO:0000329--C:fungal-type vacuole membrane |