dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016572
Uniprot Accession Q12250; RPN5_YEAST; D6VRK1;
Genbank Protein ID NP_010134.1;
Genbank Nucleotide ID NM_001180207.1;
Protein Name 26S proteasome regulatory subunit RPN5
Protein Synonyms/Alias Proteasome non-ATPase subunit 5;
Gene Name RPN5
Gene Synonyms/Alias NAS5;YDL147W;D1572;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Phosphorylation Sites
 dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
26EEFPKIDSLAQNDCNPhosphoGRID 2.020486117
95QLKLSIQYMIQKVMEPhosphoGRID 2.0;curated19823750; 19795423; 22817900
194SILKGDYSQATVLSRcurated22817900; 19547744
200YSQATVLSRKILKKTcurated22817900; 19547744
298KKLESQESLVKLFTTcurated22817900
Sequence
(Fasta)		MSRDAPIKAD KDYSQILKEE FPKIDSLAQN DCNSALDQLL VLEKKTRQAS DLASSKEVLA 60
KIVDLLASRN KWDDLNEQLT LLSKKHGQLK LSIQYMIQKV MEYLKSSKSL DLNTRISVIE 120
TIRVVTENKI FVEVERARVT KDLVEIKKEE GKIDEAADIL CELQVETYGS MEMSEKIQFI 180
LEQMELSILK GDYSQATVLS RKILKKTFKN PKYESLKLEY YNLLVKISLH KREYLEVAQY 240
LQEIYQTDAI KSDEAKWKPV LSHIVYFLVL SPYGNLQNDL IHKIQNDNNL KKLESQESLV 300
KLFTTNELMR WPIVQKTYEP VLNEDDLAFG GEANKHHWED LQKRVIEHNL RVISEYYSRI 360
TLLRLNELLD LTESQTETYI SDLVNQGIIY AKVNRPAKIV NFEKPKNSSQ LLNEWSHNVD 420
ELLEHIETIG HLITKEEIMH GLQAK 446
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0647--Proteasome
KW-1185--Reference proteome
Interpro

IPR000717--PCI_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE
Pfam

PF01399--PCI
Gene Ontology

GO:0008180--C:COP9 signalosome
GO:0031595--C:nuclear proteasome complex
GO:0000502--C:proteasome complex
GO:0008541--C:proteasome regulatory particle, lid subcomplex
GO:0034515--C:proteasome storage granule
GO:0010388--P:cullin deneddylation
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006511--P:ubiquitin-dependent protein catabolic process