dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016568
Uniprot Accession Q12242; RUP1_YEAST; D6W2J5;
Genbank Protein ID NP_014781.1;
Genbank Nucleotide ID NM_001183557.1;
Protein Name UBA domain-containing protein RUP1
Protein Synonyms/Alias
Gene Name RUP1
Gene Synonyms/Alias YOR138C;YOR3332c;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Modulates the activity of the RSP5 HECT ubiquitin-protein ligase through its mediation of the interaction between RSP5 and the deubiquitinase UBP2. Involved in regulation of cell wall homeostasis.
Phosphorylation Sites
dbPAF PTMs: 10
PositionPeptidesSourceReferences ( PMIDs )
56MGEENDGSQPRISENdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988
101YDDDEDITDERSGSNcurated26040289
107ITDERSGSNSTSGCRcurated25315811
123TAQNYDRYSISETSIPhosphoGRID 2.019779198
126NYDRYSISETSIPPPdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19779198; 19366988; 22369663;
128DRYSISETSIPPPSYcurated25315811
129RYSISETSIPPPSYSdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19779198; 19366988; 22369663
134ETSIPPPSYSIVQHNcurated25315811
633FAEDDQNSLKTLRSQcurated22369663
669DNDDDIDSDN-----PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;curated19684113; 19823750; 19795423; 21081558; 19060867; 25882841;
Sequence
(Fasta)
MMDNQAVKSL LEMGIPHEVA VDALQRTGGN LEAAVNFIFS NELPEQAEMG EENDGSQPRI 60
SENKIVAGTK PCDVPNNGDQ DIDMPDVSGV DVDYDDDEDI TDERSGSNST SGCRVTAQNY 120
DRYSISETSI PPPSYSIVQH NEFKSNVGDP TVVLPLPLNS LIESYFGLFA LLTAVYFPHV 180
FLKPDFKDLN YRADWFKGSS FTEPKYRLAY CEAEDGSTTS EIVLASGPNE GLQPHLLWQL 240
QKLISVVNTR KCERAFVSAK VFTSSLEPQL RSKLADSEHL YEVLPAFIKS LAVDLEMCPG 300
IRDRETRSLF ISSALHTPNK NEPPMETFLS LFHFLPEEYD SNLYKMFNVL LYPEEEEEEE 360
DVIRGGEQEE ARYVEPENTL KEVAPVLTIL FNELETNTES VSLPNGVDIP LEFYPQLYTK 420
QCKDQLIRHI ISKRKQARTR SRCLLQEINE LKSYQGKNIS TILESTLAYL QTIPDDANNE 480
AAKQIASLKD TLNSARAAKM EEYKDLASKL HGEWNLSHPE THIINTAKQL GLIENPYILT 540
MAALSPYSYF IRSRNGAWSW IQSNTLGTEF KVKKCSSPSV VQEAIKHGTK YASETPLMFI 600
YCEEGKIPTE EVVAEALKSN SGCLKFAEDD QNSLKTLRSQ FFDGMGDPEQ ATNNINNGND 660
NDNDDDIDSD N 672
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50030--UBA

Pfam

PF00627--UBA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:1902499--P:positive regulation of protein autoubiquitination
GO:0016579--P:protein deubiquitination