| Tag |
Content |
| dbPAF ID |
dbPAF-0016567 |
| Uniprot Accession |
Q12241; VAM3_YEAST; D6W2G5;
|
| Genbank Protein ID |
NP_014749.1;
|
| Genbank Nucleotide ID |
NM_001183525.1;
|
| Protein Name |
Syntaxin VAM3 |
| Protein Synonyms/Alias |
Vacuolar morphogenesis protein 3; |
| Gene Name |
VAM3 |
| Gene Synonyms/Alias |
PTH1;YOR106W;YOR3220W; |
| Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID |
559292 |
Functional Description
(View all) |
Required for vacuolar assembly. Provides the t-SNARE function in a late step of the vacuolar assembly. Required for homotypic vacuole membrane fusion, autophagy and fusion of biosynthetic transport vesicles with the vacuole. Required for the delivery of alpha-factor receptor-ligand complexes to the vacuole.Functional Description
Required for vacuolar assembly. Provides the t-SNARE function in a late step of the vacuolar assembly. Required for homotypic vacuole membrane fusion, autophagy and fusion of biosynthetic transport vesicles with the vacuole. Required for the delivery of alpha-factor receptor-ligand complexes to the vacuole. |
Phosphorylation Sites
|
dbPAF PTMs: 7 |
Sequence
(Fasta) | MSFFDIEAQS SKGNSQQEPQ FSTNQKTKEL SNLIETFAEQ SRVLEKECTK IGSKRDSKEL 60
RYKIETELIP NCTSVRDKIE SNILIHQNGK LSADFKNLKT KYQSLQQSYN QRKSLFPLKT 120
PISPGTSKER KDIHPRTEAV RQDPESSYIS IKVNEQSPLL HNEGQHQLQL QEEQEQQQQG 180
LSQEELDFQT IIHQERSQQI GRIHTAVQEV NAIFHQLGSL VKEQGEQVTT IDENISHLHD 240
NMQNANKQLT RADQHQRDRN KCGKVTLIII IVVCMVVLLA VLS
284Fasta Sequence
>Q12241|VAM3|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
MSFFDIEAQSSKGNSQQEPQFSTNQKTKELSNLIETFAEQSRVLEKECTKIGSKRDSKELRYKIETELIPNCTSVRDKIESNILIHQNGKLSADFKNLKTKYQSLQQSYNQRKSLFPLKTPISPGTSKERKDIHPRTEAVRQDPESSYISIKVNEQSPLLHNEGQHQLQLQEEQEQQQQGLSQEELDFQTIIHQERSQQIGRIHTAVQEVNAIFHQLGSLVKEQGEQVTTIDENISHLHDNMQNANKQLTRADQHQRDRNKCGKVTLIIIIVVCMVVLLAVLS
|
| Keyword |
KW-0002--3D-structure
KW-0072--Autophagy
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0926--Vacuole
|
| Interpro |
IPR006012--Syntaxin/epimorphin_CS
IPR010989--t-SNARE
IPR000727--T_SNARE_dom
|
| PROSITE |
PS00914--SYNTAXIN
PS50192--T_SNARE
|
| Pfam |
PF05739--SNARE
|
| Gene Ontology |
GO:0012505--C:endomembrane system
GO:0000329--C:fungal-type vacuole membrane
GO:0016021--C:integral component of membrane
GO:0031201--C:SNARE complex
GO:0005484--F:SNAP receptor activity
GO:0000149--F:SNARE binding
GO:0097352--P:autophagosome maturation
GO:0006896--P:Golgi to vacuole transport
GO:0006886--P:intracellular protein transport
GO:0034727--P:piecemeal microautophagy of nucleus
GO:0042144--P:vacuole fusion, non-autophagic
GO:0048278--P:vesicle docking
GO:0006906--P:vesicle fusion
GO:0051469--P:vesicle fusion with vacuole
|
