dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016565
Uniprot Accession Q12235; YCT1_YEAST; D6VXV3;
Genbank Protein ID NP_013045.1;
Genbank Nucleotide ID NM_001181875.1;
Protein Name High affinity cysteine transporter
Protein Synonyms/Alias
Gene Name YCT1
Gene Synonyms/Alias YLL055W;L0578;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 High affinity cysteine-specific transporter. Major contributor to cysteine transport when cysteine, at low concentrations, is provided as the sole sulfur source.
Phosphorylation Sites
 dbPAF PTMs: 14
PositionPeptidesSourceReferences ( PMIDs )
12DVKIGADSISSSDEIPhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;curated21177495; 20702584; 19779198; 21081558; 19060867; 22817900;
14KIGADSISSSDEILVPhosphoGRID 2.0;curated20702584; 26040289; 22817900
15IGADSISSSDEILVPPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 20702584; 19060867; 26040289; 22817900; 25315811
16GADSISSSDEILVPSPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 20702584; 19060867; 22817900
265IRRVQASTGSSIEQKcurated22817900
267RVQASTGSSIEQKVFcurated22817900
286FREAMKDYITWLFGLcurated24603354
288EAMKDYITWLFGLFFcurated24603354
323GGVDALGSTLVSVAGcurated24603354
324GVDALGSTLVSVAGAcurated24603354
342VVCAFIATLMLAKWKcurated24603354
496DRIQLIESENPSSIEdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
500LIESENPSSIEEGKVdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 20702584; 19779198; 19060867;
501IESENPSSIEEGKVVPhosphoGRID 2.0;UniProt;curated21177495; 20702584; 19779198; 22817900; 25315811
Sequence
(Fasta)		MSKVDVKIGA DSISSSDEIL VPSRLADVTL AFMEENDAAV PEITPEQEKK LKRKLFLTIF 60
TFVSAINLLL YMDKATLSYD SILGFFEDTG LTQNTYNTVN TLFYVGFAIG QFPGQYLAQK 120
LPLGKFLGGL LATWTILIFL SCTAYNFSGV VALRFFLGLT ESVVIPILIT TMGMFFDASE 180
RAAAQPFFFA ACMGSPIPTG FIAYGVLHIT NPSISLWKIF TIIIGGLTFI MTVVVILWFP 240
NNPADVKFFS IQERVWIIRR VQASTGSSIE QKVFKKSQFR EAMKDYITWL FGLFFLLQQL 300
ANNLPYQQNL LFEGMGGVDA LGSTLVSVAG AGFAVVCAFI ATLMLAKWKN ISALTAIFWT 360
LPALVGSIAA AALPWDNKIG ILANICMAGQ IFGIPFIIAL SWASSSASGY TKKLTRSSVS 420
LFAMGIANII SPQIWREKDS PRFLPAWIVQ IVLSFSLAPA ILLLIHFILK RRNNQRLKNY 480
DENLQNYLDR IQLIESENPS SIEEGKVVTH ENNLAVFDLT DLENETFIYP L 532
Keyword

KW-0029--Amino-acid transport
KW-1003--Cell membrane
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0325--Glycoprotein
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
Interpro

IPR011701--MFS
IPR020846--MFS_dom
PROSITE
Pfam

PF07690--MFS_1
Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0033229--F:cysteine transmembrane transporter activity
GO:0015075--F:ion transmembrane transporter activity
GO:1903712--P:cysteine transmembrane transport
GO:0042883--P:cysteine transport
GO:0034220--P:ion transmembrane transport
GO:0055085--P:transmembrane transport