dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016561
Uniprot Accession Q12229; UBX3_YEAST; D6VRQ7;
Genbank Protein ID NP_010192.1;
Genbank Nucleotide ID NM_001180150.1;
Protein Name UBX domain-containing protein 3
Protein Synonyms/Alias
Gene Name UBX3
Gene Synonyms/Alias YDL091C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway. Involved in delivery of substrates to the 26S proteasome. Also required for membrane fusion (By similarity).
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
14TFGNNDDSFIRIPGAcurated22817900; 25315811; 19547744
39GRTEDQNSNTNEPTQcurated25315811
423QYSFKLITPVPRRELcurated25315811
Sequence
(Fasta)		MDIFRHTFGN NDDSFIRIPG AFREEPPADL NGRTEDQNSN TNEPTQSRDG RLKSILHFLF 60
QAPLIVLYYL LNFIVRSSRL LKPLLRLHGF YQRKHNRLLD HSSQLHRLLE NLENEAQAVT 120
CSEGNGNNDD GSNTDSTSNN ESSGVQFSFG SLYNPENGTF SKSIMQNSYT ELLDACSEQV 180
KFGVIYLHDP LLDNHMDYVN KILCSEAFVN MIRKYQVLLW YGDVTTSEGL QVSNALKIRQ 240
YPLLGIISLK AEKKIELIAR VEGSISNYKA QDLEAIFSKN YSRLIQLRQQ RQNIEMQRLI 300
RQQQDSRYQD SLRRDQQRES ERLEQTQREQ MEREHQRIEN QWLLWRKSQL KPEPSSDKDA 360
SKVAIRLENG QRLVRKFDAS LPTEEIYAFV ELQLHDMLNS ENDTLPVYQP ANYQHQYSFK 420
LITPVPRREL DLSTKISDVS GIYPSGNIVM ERLDE 456
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
Interpro

IPR012336--Thioredoxin-like_fold
IPR006577--UAS
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom
PROSITE

PS50033--UBX
Pfam

PF00789--UBX
Gene Ontology

GO:0030136--C:clathrin-coated vesicle
GO:0044695--C:Dsc E3 ubiquitin ligase complex
GO:0030276--F:clathrin binding
GO:0072583--P:clathrin-mediated endocytosis
GO:0033523--P:histone H2B ubiquitination