dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016560
Uniprot Accession Q12224; RLM1_YEAST; D6W3S8;
Genbank Protein ID NP_015236.1;
Genbank Nucleotide ID NM_001183903.1;
Protein Name Transcription factor RLM1
Protein Synonyms/Alias
Gene Name RLM1
Gene Synonyms/Alias YPL089C;LPG19C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 May function as a transcription factor downstream of MPK1 that is subject to activation by the MPK1 mitogen-activated protein kinase pathway. Binds to the DNA sequence 5'-CTA[TA](4)TAG-3'. At least some RML1 target genes are involved in cell wall biosynthesis.
Phosphorylation Sites
 dbPAF PTMs: 20
PositionPeptidesSourceReferences ( PMIDs )
83LHEVKDPSDYGDFHKcurated24961812; 25315811
120NVKGMNQSENDDDENPhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;UniProt;curated20489023; 19779198; 21081558; 19060867; 26040406; 22369663;
164SAHMKLLSPTALISKdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 16381945; 23193290; 21177495; 20489023; 20702584;
170LSPTALISKMDGSEQcurated26040406
205DPLQISRTPQQQQQQcurated25315811
259NGRPPPISISPNKFScurated22369663; 25315811
261RPPPISISPNKFSKPcurated22369663; 24961812; 25521595; 25315811
299DNSNYTQSPSNSLEDPhosphoGRID 2.0;PhosphoPep 2.0;curated20489023; 19060867; 24961812
368IMKENKTSRSSKISPcurated19823750
370KENKTSRSSKISPLSdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 17330950; 21177495; 20702584;
371ENKTSRSSKISPLSAdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 20702584; 19060867; 19366988;
374TSRSSKISPLSASASdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 18407956; 16381945; 23193290; 21177495; 20489023;
377SSKISPLSASASGPLdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 18407956; 16381945; 23193290; 21177495; 20489023;
379KISPLSASASGPLTLPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 19684113; 19779198; 19060867; 22817900; 19823750;
381SPLSASASGPLTLQKcurated24961812
385ASASGPLTLQKGNNGcurated24961812
427YPFGSGSSPLFSATQPhosphoGRID 2.012410835
439ATQPYIATPLQPSNIPhosphoGRID 2.012410835
503ETSNGPPTGSLPSKFPhosphoPep 2.019060867
668FNFSTDISGEKNSSKcurated24961812
Sequence
(Fasta)		MGRRKIEIQR ISDDRNRAVT FIKRKAGLFK KAHELSVLCQ VDIAVIILGS NNTFYEFSSV 60
DTNDLIYHYQ NDKNLLHEVK DPSDYGDFHK SASVNINQDL LRSSMSNKPS KSNVKGMNQS 120
ENDDDENNDE DDDDHGNFER NSNMHSNKKA SDKNIPSAHM KLLSPTALIS KMDGSEQNKR 180
HPENALPPLQ HLKRLKPDPL QISRTPQQQQ QQNISRPYHS SMYNLNQPSS SSSSPSTMDF 240
PKLPSFQNSS FNGRPPPISI SPNKFSKPFT NASSRTPKQE HKINNSGSNN NDNSNYTQSP 300
SNSLEDSIQQ TVKARRKLSA RPVLRVRIPN NNFSSNSAIP SEPSSASSTS ANGNSMGSSQ 360
IMKENKTSRS SKISPLSASA SGPLTLQKGN NGRMVIKLPN ANAPNGSNNG NGSNNNNHPY 420
PFGSGSSPLF SATQPYIATP LQPSNIPGGP FQQNTSFLAQ RQTQQYQQMS FKKQSQTVPL 480
TTTLTGRPPS TFSGPETSNG PPTGSLPSKF VHDLMSNSPN VSSISMFPDW SMGPNSAKPG 540
NTNNPGTFPP VQTAVNNGNS SNISSTNNTN NNNNNNNNNS SNNNSNNGND NNSNNSNNSY 600
YSNNEDAPVN GAAISEHTTD GDSNNQSNSS TYDAAATAYN GNTGLTPYIN TAQTPLGTKF 660
FNFSTDISGE KNSSKI 677
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR002100--TF_MADSbox
PROSITE

PS00350--MADS_BOX_1
PS50066--MADS_BOX_2
Pfam

PF00319--SRF-TF
Gene Ontology

GO:0005634--C:nucleus
GO:0008301--F:DNA binding, bending
GO:0051019--F:mitogen-activated protein kinase binding
GO:0043565--F:sequence-specific DNA binding
GO:0000982--F:transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0036003--P:positive regulation of transcription from RNA polymerase II promoter in response to stress
GO:0007165--P:signal transduction
GO:0006351--P:transcription, DNA-templated