Tag |
Content |
dbPAF ID |
dbPAF-0016557 |
Uniprot Accession |
Q12220; UTP12_YEAST; D6VYC4; Q05386; |
Genbank Protein ID |
NP_013230.1; |
Genbank Nucleotide ID |
NM_001182016.1; |
Protein Name |
U3 small nucleolar RNA-associated protein 12 |
Protein Synonyms/Alias |
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Gene Name |
DIP2 |
Gene Synonyms/Alias |
UTP12;YLR129W;L3116;L9233.1; |
Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
NCBI Taxa ID |
559292 |
Functional Description (View all) |
Involved in nucleolar processing of pre-18S ribosomal RNA.Functional Description
Involved in nucleolar processing of pre-18S ribosomal RNA.
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Phosphorylation Sites
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dbPAF PTMs: 3 |
Sequence (Fasta) | MVKSYQRFEQ AAAFGVIASN ANCVWIPASS GNSNGSGPGQ LITSALEDVN IWDIKTGDLV 60 SKLSDGLPPG ASDARGAKPA ECTYLEAHKD TDLLAVGYAD GVIKVWDLMS KTVLLNFNGH 120 KAAITLLQFD GTGTRLISGS KDSNIIVWDL VGEVGLYKLR SHKDSITGFW CQGEDWLIST 180 SKDGMIKLWD LKTHQCIETH IAHTGECWGL AVKDDLLITT GTDSQVKIWK LDIENDKMGG 240 KLTEMGIFEK QSKQRGLKIE FITNSSDKTS FFYIQNADKT IETFRIRKEE EIARGLKKRE 300 KRLKEKGLTE EEIAKSIKES YSSFILHPFQ TIRSLYKIKS ASWTTVSSSK LELVLTTSSN 360 TIEYYSIPYE KRDPTSPAPL KTHTIELQGQ RTDVRSIDIS DDNKLLATAS NGSLKIWNIK 420 THKCIRTFEC GYALTCKFLP GGLLVILGTR NGELQLFDLA SSSLLDTIED AHDAAIWSLD 480 LTSDGKRLVT GSADKTVKFW DFKVENSLVP GTKNKFLPVL KLHHDTTLEL TDDILCVRVS 540 PDDRYLAISL LDNTVKVFFL DSMKFYLSLY GHKLPVLSID ISFDSKMIIT SSADKNIKIW 600 GLDFGDCHKS LFAHQDSIMN VKFLPQSHNF FSCSKDAVVK YWDGEKFECI QKLYAHQSEV 660 WALAVATDGG FVVSSSHDHS IRIWEETEDQ VFLEEEKEKE LEEQYEDTLL TSLEEGNGDD 720 AFKADASGEG VEDEASGVHK QTLESLKAGE RLMEALDLGI AEIEGLEAYN RDMKLWQRKK 780 LGEAPIKPQG NAVLIAVNKT PEQYIMDTLL RIRMSQLEDA LMVMPFSYVL KFLKFIDTVM 840 QNKTLLHSHL PLICKNLFFI IKFNHKELVS QKNEELKLQI NRVKTELRSA LKSTEDDLGF 900 NVQGLKFVKQ QWNLRHNYEF VDEYDQQEKE SNSARKRVFG TVI
944Fasta Sequence
>Q12220|DIP2|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) MVKSYQRFEQAAAFGVIASNANCVWIPASSGNSNGSGPGQLITSALEDVNIWDIKTGDLVSKLSDGLPPGASDARGAKPAECTYLEAHKDTDLLAVGYADGVIKVWDLMSKTVLLNFNGHKAAITLLQFDGTGTRLISGSKDSNIIVWDLVGEVGLYKLRSHKDSITGFWCQGEDWLISTSKDGMIKLWDLKTHQCIETHIAHTGECWGLAVKDDLLITTGTDSQVKIWKLDIENDKMGGKLTEMGIFEKQSKQRGLKIEFITNSSDKTSFFYIQNADKTIETFRIRKEEEIARGLKKREKRLKEKGLTEEEIAKSIKESYSSFILHPFQTIRSLYKIKSASWTTVSSSKLELVLTTSSNTIEYYSIPYEKRDPTSPAPLKTHTIELQGQRTDVRSIDISDDNKLLATASNGSLKIWNIKTHKCIRTFECGYALTCKFLPGGLLVILGTRNGELQLFDLASSSLLDTIEDAHDAAIWSLDLTSDGKRLVTGSADKTVKFWDFKVENSLVPGTKNKFLPVLKLHHDTTLELTDDILCVRVSPDDRYLAISLLDNTVKVFFLDSMKFYLSLYGHKLPVLSIDISFDSKMIITSSADKNIKIWGLDFGDCHKSLFAHQDSIMNVKFLPQSHNFFSCSKDAVVKYWDGEKFECIQKLYAHQSEVWALAVATDGGFVVSSSHDHSIRIWEETEDQVFLEEEKEKELEEQYEDTLLTSLEEGNGDDAFKADASGEGVEDEASGVHKQTLESLKAGERLMEALDLGIAEIEGLEAYNRDMKLWQRKKLGEAPIKPQGNAVLIAVNKTPEQYIMDTLLRIRMSQLEDALMVMPFSYVLKFLKFIDTVMQNKTLLHSHLPLICKNLFFIIKFNHKELVSQKNEELKLQINRVKTELRSALKSTEDDLGFNVQGLKFVKQQWNLRHNYEFVDEYDQQEKESNSARKRVFGTVI
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Keyword |
KW-0181--Complete proteome KW-0539--Nucleus KW-1185--Reference proteome KW-0677--Repeat KW-0687--Ribonucleoprotein KW-0690--Ribosome biogenesis KW-0698--rRNA processing KW-0853--WD repeat
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Interpro |
IPR020472--G-protein_beta_WD-40_rep IPR007148--SSU_processome_Utp12 IPR015943--WD40/YVTN_repeat-like_dom IPR001680--WD40_repeat IPR019775--WD40_repeat_CS IPR017986--WD40_repeat_dom
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PROSITE |
PS00678--WD_REPEATS_1 PS50082--WD_REPEATS_2 PS50294--WD_REPEATS_REGION
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Pfam |
PF04003--Utp12 PF00400--WD40
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Gene Ontology |
GO:0005730--C:nucleolus GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome GO:0032040--C:small-subunit processome GO:0030515--F:snoRNA binding GO:0000480--P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5 8S rRNA, L--U-rRNA) GO:0000447--P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5 8S rRNA an-- LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5 8S rRNA, L--U-rRNA) GO:0000472--P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5 8S rRNA, L--U-rRNA) GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5 8S rRNA, L--U-rRNA)
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