dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0016550 | ||||||||
| Uniprot Accession | Q12211; PUS1_YEAST; D6W3F8; | ||||||||
| Genbank Protein ID | NP_015112.1; | ||||||||
| Genbank Nucleotide ID | NM_001184026.1; | ||||||||
| Protein Name | tRNA pseudouridine synthase 1 | ||||||||
| Protein Synonyms/Alias | tRNA pseudouridylate synthase 1;tRNA-uridine isomerase 1; | ||||||||
| Gene Name | PUS1 | ||||||||
| Gene Synonyms/Alias | YPL212C; | ||||||||
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) | ||||||||
| NCBI Taxa ID | 559292 | ||||||||
| Functional Description (View all) |
Formation of pseudouridine at positions 27 and 28 in the anticodon stem and loop of transfer RNAs; at positions 34 and 36 of intron-containing precursor tRNA(Ile) and at position 35 in the intron-containing tRNA(Tyr). | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MSEENLRPAY DDQVNEDVYK RGAQSKLTKA RKADFDDEKD KKKDNDKHID KRPKSGPRLD 60 ENGNPLPKEP RLPKRKVAVM VGYCGTGYHG MQYNPPNPTI ESALFKAFVE AGAISKDNSN 120 DLKKNGFMRA ARTDKGVHAG GNLISLKMII EDPDIKQKIN EKLPEGIRVW DIERVNKAFD 180 CRKMCSSRWY EYLLPTYSLI GPKPGSILYR DIEESKTELP GVLDEDLESK EFWEEFKKDA 240 NEKFSTEEIE AILAYVPPAR DEFDINEELY QKVKKYKQLE NAHRRRYRIS AAKLAKFRAS 300 TSQYLGAHNF HNFTLGKDFK EPSAIRFMKD IKVSDPFVIG DAQTEWISIK IHGQSFMLHQ 360 IRKMVSMATL ITRCGCPVER ISQAYGQQKI NIPKAPALGL LLEAPVFEGY NKRLEQFGYK 420 AIDFSKYQDE VDKFKMKHIY DKIYKEEVDE NVFNAFFSYI DSFNKVTGAQ GEETADKSGP 480 AVQKSIFEFL TAKGIPGLTD APESNKKIKQ RKRMEEEEAA SKKAEISSTT QSNEPEVQPE 540 AAAN 545 |
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| Keyword | KW-0181--Complete proteome |
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| Interpro | IPR020103--PsdUridine_synth_cat_dom |
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| PROSITE | |||||||||
| Pfam | PF01416--PseudoU_synth_1 |
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| Gene Ontology | GO:0005654--C:nucleoplasm |