dbPAF Protein Information
| Tag | Content | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0016547 | ||||||||||||
| Uniprot Accession | Q12207; NCE2_YEAST; D6W4E6; | ||||||||||||
| Genbank Protein ID | NP_015475.1; | ||||||||||||
| Genbank Nucleotide ID | NM_001184246.1; | ||||||||||||
| Protein Name | Non-classical export protein 2 | ||||||||||||
| Protein Synonyms/Alias | |||||||||||||
| Gene Name | NCE102 | ||||||||||||
| Gene Synonyms/Alias | NCE2;RTG2S2;YPR149W;P9659.2; | ||||||||||||
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) | ||||||||||||
| NCBI Taxa ID | 559292 | ||||||||||||
| Functional Description (View all) |
Involved in membrane organization. Required for the formation of membrane compartments of CAN1 (MCCs), localization of CAN1 at the MCCs and subsequent invagination of the plasma membrane at the MCCs sites. Involved in eisosome organization and might act as a sensor of sphingolipids that regulates plasma membrane function. Involved in a novel pathway of export of proteins that lack a cleavable signal sequence. It may be an accessory subunit to an essential core component of the non-classical export machinery. Non-classical export pathway functions also as an alternative clearance/detoxification pathway to eliminate damaged material, when the basic repair pathway is not sufficient. | ||||||||||||
| Phosphorylation Sites |
dbPAF PTMs: 2
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| Sequence (Fasta) | MLALADNILR IINFLFLVIS IGLISSLLNT QHRHSSRVNY CMFACAYGIF TDSLYGVFAN 60 FIEPLAWPLV LFTLDFLNFV FTFTAGTVLA VGIRAHSCNN SSYVDSNKIT QGSGTRCRQA 120 QAAVAFLYFS CAIFLAKTLM SVFNMISNGA FGSGSFSKRR RTGQVGVPTI SQV 174 |
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| Keyword | KW-1003--Cell membrane |
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| Interpro | IPR008253--Marvel |
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| PROSITE | |||||||||||||
| Pfam | PF01284--MARVEL |
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| Gene Ontology | GO:0033101--C:cellular bud membrane |