dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0016542 |
| Uniprot Accession | Q12199; TIP41_YEAST; D6W449; |
| Genbank Protein ID | NP_015365.1; |
| Genbank Nucleotide ID | NM_001184137.1; |
| Protein Name | Type 2A phosphatase activator TIP41 |
| Protein Synonyms/Alias | PP2A phosphatase activator TIP41;TAP42-interacting protein 1; |
| Gene Name | TIP41 |
| Gene Synonyms/Alias | YPR040W;YP3085.04; |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID | 559292 |
| Functional Description (View all) |
Involved in negative regulation of the TOR signaling pathway in response to type of available nitrogen source. Indirectly activates the PP2A phosphatase SIT4 via interaction with its suppressor TAP42. This interaction is enhanced under nitrogen limitation conditions. Also has a role in regulation of NPR1 in response to nitrogen limitation. |
| Phosphorylation Sites |
dbPAF PTMs: 4 |
| Sequence (Fasta) | MSKRNTPPLR SSGINTIQIN AAREMHAQTV RARRMPMPTS GITTPSVQPT AAPATPPRHI 60 CNNPNNPQCL HCGSVIIPSP RATLPLEDNP SISINDWTIS SRKKPILNSQ ELDIWENEKL 120 KGLTLPEMIF GNNYIRIENS KQHWSIEFNA LDALKEVQLQ DSGIRVAYSN DWINSKKRQN 180 STNGAQRFTN DVNDDSLNII HKYDWTYTTR YKGTESSPES KFRLDNDQKL PLDKLAVHDK 240 ILFYDDMILF EDELADNGIS ILNVKIRVMN ERLLLLSRFF LRVDDVLVRV YDTRIYVEFD 300 ENVVIRESKE FEGKYQDVLA KHRLSQSHDP KAALRDSNWV AQNTPMIKRQ CEIIQF 357 |
| Keyword | KW-0181--Complete proteome |
| Interpro | IPR007303--TIP41-like |
| PROSITE | |
| Pfam | PF04176--TIP41 |
| Gene Ontology | GO:0005737--C:cytoplasm |