dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016530
Uniprot Accession Q12176; MAK21_YEAST; D6VS46;
Genbank Protein ID NP_010345.3;
Genbank Nucleotide ID NM_001180368.3;
Protein Name Ribosome biogenesis protein MAK21
Protein Synonyms/Alias Maintenance of killer protein 21;Nucleolar complex protein 1;
Gene Name MAK21
Gene Synonyms/Alias NOC1;YDR060W;D4237;YD9609.14;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Required for 60S ribosomal subunit synthesis.
Phosphorylation Sites
 dbPAF PTMs: 32 (View all)
PositionPeptidesSourceReferences ( PMIDs )
2------MSENNGNPLcurated24961812; 19547744
13GNPLDLSSLRNKISScurated19823750
19SSLRNKISSKLRDNNcurated19823750
62EALALGASEEDLKLIdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 18407956; 16381945; 23193290; 21126336; 19779198;
73LKLIQGLSDDDDAKSdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 17563356; 18407956; 16381945; 23193290; 21177495;
80SDDDDAKSEQEFDAVdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 17563356; 18407956; 16381945; 23193290; 21177495;
127DDDIEEESTSSKESKdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;SysPTM 2.0;curated17330950; 16381945; 23193290; 21126336; 21081558; 19366988;
128DDIEEESTSSKESKIcurated19823750; 25521595; 25315811
129DIEEESTSSKESKIPPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 26040289; 22817900; 19823750; 25521595;
130IEEESTSSKESKIPAPHOSIDA;curated21081558; 22817900; 19823750; 19795423; 25315811
133ESTSSKESKIPAQEKPhosphoGRID 2.0;PHOSIDA;curated19823750; 19795423; 21081558; 22817900
159IEKTSQESIDNGSEQcurated20377248
164QESIDNGSEQEENTVPHOSIDA;curated21081558; 22817900; 19795423; 20377248
170GSEQEENTVEEANLScurated22817900
177TVEEANLSSDQEPESPHOSIDA;curated21081558; 22817900; 19795423; 20377248
178VEEANLSSDQEPESEPHOSIDA;curated21081558; 22817900; 19795423; 20377248
204GGLITQTTIISSDKLcurated22817900; 19547744
275SSQAKFMSQILSDGTPhosphoGRID 2.0;UniProt;curated19779198; 22817900
700PQIKNLLTNTPVDYEPhosphoGRID 2.021126336
706LTNTPVDYEYESDAEdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.017330950; 16381945; 23193290; 19060867; 19366988
Sequence
(Fasta)		MSENNGNPLD LSSLRNKISS KLRDNNSKKA KKTHKGKDVK ASSNSKKVNE DIRREALALG 60
ASEEDLKLIQ GLSDDDDAKS EQEFDAVADE DADDKGFKND LQNFMKNVGF DQHKLEDVDD 120
DDIEEESTSS KESKIPAQEK EHAQSNIASS TIEKTSQESI DNGSEQEENT VEEANLSSDQ 180
EPESESAEKE KKEEKDGGLI TQTTIISSDK LIIPYDKPWY EIPLDPQVGQ NDDVEELSKE 240
QIEKLFERGK QTLEADNQTY YEEFTKDSSQ AKFMSQILSD GTLNDKISAV TLLIQDSPLH 300
NTKSLETLVS YCGKKSRNSA LQSLNALKDL FLNGLLPNRK LRYFKNQPGL SMMLNKKTLA 360
IFYFEDYLKK LFFRVLEVLE VLSHDPIIHV RLQILNHVFD LLTNQPEQEF NLLRLGVNKI 420
GDIDSKVSSK ASYLLLKLEQ AHPNMKSIVI DAIVDIALRP NADYHTTYYS VITLNQTILK 480
RSEDSVANKL VKTYFTLFEK FLINTDKDNT NGVVKSNSKS YEEKRKKNFK KGKHGGKSVK 540
IEKTENEVLD EKNSKLFSAL LTGINRAFPF AQIPASVYEV HMETLFKITH SSNFNTSIQA 600
LVLINQVTVK AKLNSDRYYR TLYESLFDPR LVNSSKQGIY LNLLYKSLKQ DALNVERVEA 660
FVKRILQVCS HWLNVGTITG FFFLLIQLAK TVPQIKNLLT NTPVDYEYES DAEEEQGDKD 720
IKRKEYDGRK RDPKFANAEK SSLWEINNFI NHFHPTVKTY ANAYVTGETE QIAKPDLGLF 780
TLSHFLDRFV YRSAKQTNTA RGTSIMQPLF SGSRVNDSVL VKASDIMHDQ GPVNTEDWLT 840
KKVEDIKPED KFFYQYFTTK KTADGKGKKS NKASNFDSDD EMDENEIWSA LVKSRPDVED 900
DSDDSELDFA EDDFSDSTSD DEPKLDAIDD EDAKSEGSQE SDQEEGLDED IFYSFDGEQD 960
NSDKKRSFAE SSEEDESSEE EKEEEENKEV SAKRAKKKQR KNMLKSLPVF ASADDYAQYL 1020
DQDSD 1026
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0690--Ribosome biogenesis
Interpro

IPR016024--ARM-type_fold
IPR005612--CCAAT-binding_factor
PROSITE
Pfam

PF03914--CBF
Gene Ontology

GO:0030690--C:Noc1p-Noc2p complex
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0030687--C:preribosome, large subunit precursor
GO:0042802--F:identical protein binding
GO:0000027--P:ribosomal large subunit assembly
GO:0042273--P:ribosomal large subunit biogenesis