dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016528
Uniprot Accession Q12172; YRR1_YEAST; D6W2M0;
Genbank Protein ID NP_014805.3;
Genbank Nucleotide ID NM_001183581.3;
Protein Name Zinc finger transcription factor YRR1
Protein Synonyms/Alias Pleiotropic drug-resistance protein 2;
Gene Name YRR1
Gene Synonyms/Alias PDR2;YOR162C;O3571;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Transcription factor involved in the regulation of multidrug resistance genes. Acts in concert with YRR1.
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
155RGSTETSSPLPDGVIdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 25315811
727KQELDPQSDNPSSEAcurated25315811
Sequence
(Fasta)		MKRRSDALLG SFQATNVTPP SDNSNSTAGG ANGSNSGTPT STSGKKRNKL IKSCGFCRRR 60
KLRCDQQKPM CSTCISRNLT TCQYAEEFNK NIEKKATYGP YPNADLLKKV EELENKIRIL 120
EAEKNTNSSA SSMYTSPNFP PLGTSVGRGS TETSSPLPDG VINPYADRYY LQSKHSGRST 180
LYGPTSMRTQ IANSNWGFIE KYKQLWAKVK VERNKWKQNN QKTMCRELGL LDESDWQPDP 240
LIKQICRFLP SYNKALSILD DFFNDGACNE INVILDKAKV RRDFLDYFMP EKEVKAEGDR 300
SIVYILSNPK KNYYKAAVIL LILCLKYFHT DVPTPIEKFF TLLKGASTAK VFYIERAQML 360
ILFYYHRETY SFGGDGSDLV NINECLVTTV TTIGLHLNIR ETFKEHEVFM GSIESLENVW 420
LMAIFIDYNI SCNVGRPLLI NKFYLDENQD HCILNSKSKT YEGKLKRYLK LTRPMLLTLY 480
DRDKFPDLKA YSKRIINFVE EELGPLGHYT GENISEEVPL RESRILSMAV GLLLSFYALI 540
HSVLKVRNIE SKNNTFQLVL INFSIIVNTT IRCYRIDKAL YPEKFEASNP HLPPHMALSM 600
SLTAGLFSKT LVFFCSLIYF KLTLFENGLC LSNDMEVGWS DLTKLTVPLD KDLSLGTAMS 660
LYSSIFDRLF TVGNKELIRT MHRSSQFVIE LAIERTYRTI LGNVIEFRKL TEETWLAQIK 720
QELDPQSDNP SSEAKIVSDR QRDLSLAVPT PTPSIIPMLP SPGETKNHAK SQSEIIQMLT 780
DEFWANYNSG WEELINQSEF STLFDDYKDN 811
Keyword

KW-0010--Activator
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
Interpro

IPR001138--Zn2-C6_fun-type_DNA-bd
PROSITE

PS00463--ZN2_CY6_FUNGAL_1
PS50048--ZN2_CY6_FUNGAL_2
Pfam

PF00172--Zn_clus
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981--F:RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043619--P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0006351--P:transcription, DNA-templated