dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016522
Uniprot Accession Q12159; YRA1_YEAST; D6VT14;
Genbank Protein ID NP_010669.1;
Genbank Nucleotide ID NM_001180689.1;
Protein Name RNA annealing protein YRA1
Protein Synonyms/Alias
Gene Name YRA1
Gene Synonyms/Alias YDR381W;D9481.2;D9509.1;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 RNA-binding RNA annealing protein. May have a role in pre-mRNA metabolism. Component the TREX complex, which operates in coupling transcription elongation to mRNA export.
Phosphorylation Sites
 dbPAF PTMs: 10
PositionPeptidesSourceReferences ( PMIDs )
2------MSANLDKSLcurated26040289
8MSANLDKSLDEIIGSdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;SysPTM 2.0;UniProt;curated15665377; 16381945; 23193290; 19823750; 19795423; 21081558;
15SLDEIIGSNKAGSNRcurated25315811
58RGPIRKNTRAPPNAVcurated22817900; 19547744
74RVAKLLDTTREVKVNPhosphoGRID 2.021126336
100AVREFFASQVGGVQRdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988
142AVERFNGSPIDGGRScurated22369663; 25315811
149SPIDGGRSRLRLNLIcurated22369663
166PNQRPVKSLADRIKAPhosphoGRID 2.0;curated19823750; 19795423; 22817900
211REKPAKKSLEDLDKEPhosphoGRID 2.0;curated19779198; 26040289; 22817900; 25521595; 25315811; 19547744
Sequence
(Fasta)		MSANLDKSLD EIIGSNKAGS NRARVGGTRG NGPRRVGKQV GSQRRSLPNR RGPIRKNTRA 60
PPNAVARVAK LLDTTREVKV NVEGLPRDIK QDAVREFFAS QVGGVQRVLL SYNERGQSTG 120
MANITFKNGE LARRAVERFN GSPIDGGRSR LRLNLIVDPN QRPVKSLADR IKAMPQKGGN 180
APRPVKRGPN RKAAMAKSQN KPKREKPAKK SLEDLDKEMA DYFEKK 227
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0694--RNA-binding
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR012677--Nucleotide-bd_a/b_plait
IPR000504--RRM_dom
PROSITE

PS50102--RRM
Pfam

PF00076--RRM_1
Gene Ontology

GO:0000346--C:transcription export complex
GO:1990119--F:ATP-dependent RNA helicase inhibitor activity
GO:0000166--F:nucleotide binding
GO:0003723--F:RNA binding
GO:0006406--P:mRNA export from nucleus
GO:1902281--P:negative regulation of ATP-dependent RNA helicase activity
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
GO:0006283--P:transcription-coupled nucleotide-excision repair