dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016497
Uniprot Accession Q12122; HOSM_YEAST; D6VRL8; E9P8Z7;
Genbank Protein ID NP_010151.1;
Genbank Nucleotide ID NM_001180190.1;
Protein Name Homocitrate synthase, mitochondrial
Protein Synonyms/Alias
Gene Name LYS21
Gene Synonyms/Alias YDL131W;D2195;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
217ELIRTLKSVVSCDIEdbPTM 3.018407956; 16381945; 23193290
332KAILANPSTYEILDPdbPTM 3.018407956; 16381945; 23193290
333AILANPSTYEILDPHdbPTM 3.018407956; 16381945; 23193290
399LNIDDVDSIIKDFHAPhosphoPep 2.019060867
409KDFHAELSTPLLKPVdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated17287358; 17563356; 18407956; 16381945; 23193290; 17330950;
410DFHAELSTPLLKPVNdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17287358; 17563356; 18407956; 16381945; 23193290; 17330950;
420LKPVNKGTDDDNIDIPHOSIDA;curated21081558; 22369663; 22817900; 19795423; 24961812; 25315811
428DDDNIDISNGHVSKKPHOSIDA;curated21081558; 26040289; 22369663; 22817900; 19795423; 25315811
433DISNGHVSKKAKVTKcurated22369663; 22817900
Sequence
(Fasta)		MSENNEFQSV TESTTAPTTS NPYGPNPADY LSNVKNFQLI DSTLREGEQF ANAFFDTEKK 60
IEIARALDDF GVDYIELTSP VASEQSRKDC EAICKLGLKA KILTHIRCHM DDARVAVETG 120
VDGVDVVIGT SKFLRQYSHG KDMNYIAKSA VEVIEFVKSK GIEIRFSSED SFRSDLVDLL 180
NIYKTVDKIG VNRVGIADTV GCANPRQVYE LIRTLKSVVS CDIECHFHND TGCAIANAYT 240
ALEGGARLID VSVLGIGERN GITPLGGLMA RMIVAAPDYV RSKYKLHKIR DIENLVADAV 300
EVNIPFNNPI TGFCAFTHKA GIHAKAILAN PSTYEILDPH DFGMKRYIHF ANRLTGWNAI 360
KSRVDQLNLN LTDDQIKEVT AKIKKLGDVR PLNIDDVDSI IKDFHAELST PLLKPVNKGT 420
DDDNIDISNG HVSKKAKVTK 441
Keyword

KW-0028--Amino-acid biosynthesis
KW-0181--Complete proteome
KW-0457--Lysine biosynthesis
KW-0496--Mitochondrion
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
KW-0809--Transit peptide
Interpro

IPR002034--AIPM/Hcit_synth_CS
IPR013785--Aldolase_TIM
IPR011872--Homocitrate_synth_fun/arc
IPR000891--PYR_CT
PROSITE

PS00815--AIPM_HOMOCIT_SYNTH_1
PS00816--AIPM_HOMOCIT_SYNTH_2
PS50991--PYR_CT
Pfam

PF00682--HMGL-like
Gene Ontology

GO:0005739--C:mitochondrion
GO:0005634--C:nucleus
GO:0004410--F:homocitrate synthase activity
GO:0019878--P:lysine biosynthetic process via aminoadipic acid