dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016495
Uniprot Accession Q12118; SGT2_YEAST; D6W273;
Genbank Protein ID NP_014649.1;
Genbank Nucleotide ID NM_001183426.1;
Protein Name Small glutamine-rich tetratricopeptide repeat-containing protein 2
Protein Synonyms/Alias SGT/UBP;Viral protein U-binding protein;
Gene Name SGT2
Gene Synonyms/Alias YOR007C;UNF346;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Co-chaperone that binds to the molecular chaperone Hsp70 (SSA1 and SSA2). Regulates Hsp70 ATPase activity (By similarity). Required for recovery from heat shock.
Phosphorylation Sites
 dbPAF PTMs: 14
PositionPeptidesSourceReferences ( PMIDs )
52GFEREAVSGILGKSEdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 22369663; 22817900;
147ANRAAAHSSLKEYDQcurated25315811
148NRAAAHSSLKEYDQAcurated25315811
161QAVKDAESAISIDPScurated25315811
168SAISIDPSYFRGYSRcurated19823750
169AISIDPSYFRGYSRLcurated19823750
174PSYFRGYSRLGFAKYcurated19823750
181SRLGFAKYAQGKPEEPhosphoPep 2.019060867
228QSLNLEKTVPEQSRDcurated25315811
233EKTVPEQSRDADVDAcurated25315811
278QAAQKMMSNPGAMQNPhosphoGRID 2.021126336
304QMAEGFASGGGTPNLcurated26040289; 22369663
308GFASGGGTPNLSDLMdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988
312GGGTPNLSDLMNNPAdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
Sequence
(Fasta)		MSASKEEIAA LIVNYFSSIV EKKEISEDGA DSLNVAMDCI SEAFGFEREA VSGILGKSEF 60
KGQHLADILN SASRVPESNK KDDAENVEIN IPEDDAETKA KAEDLKMQGN KAMANKDYEL 120
AINKYTEAIK VLPTNAIYYA NRAAAHSSLK EYDQAVKDAE SAISIDPSYF RGYSRLGFAK 180
YAQGKPEEAL EAYKKVLDIE GDNATEAMKR DYESAKKKVE QSLNLEKTVP EQSRDADVDA 240
SQGASAGGLP DLGSLLGGGL GGLMNNPQLM QAAQKMMSNP GAMQNIQKMM QDPSIRQMAE 300
GFASGGGTPN LSDLMNNPAL RNMAGNLFGG AGAQSTDETP DNENKQ 347
Keyword

KW-0002--3D-structure
KW-0143--Chaperone
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
Interpro

IPR032374--SGTA_dimer
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR001440--TPR_1
IPR019734--TPR_repeat
PROSITE

PS50005--TPR
PS50293--TPR_REGION
Pfam

PF16546--SGTA_dimer
PF00515--TPR_1
PF13414--TPR_11
Gene Ontology

GO:0072380--C:TRC complex
GO:0032947--F:protein complex scaffold
GO:0006620--P:posttranslational protein targeting to membrane
GO:0009408--P:response to heat