dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016484
Uniprot Accession Q12100; RTK1_YEAST; D6VRW6;
Genbank Protein ID NP_010259.1;
Genbank Nucleotide ID NM_001180084.1;
Protein Name Probable serine/threonine-protein kinase RTK1
Protein Synonyms/Alias Ribosome biogenesis and tRNA synthetase-associated kinase 1;
Gene Name RTK1
Gene Synonyms/Alias YDL025C;D2810;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Probable serine/threonine-protein kinase that may be involved in ribosome biogenesis.
Phosphorylation Sites
 dbPAF PTMs: 39 (View all)
PositionPeptidesSourceReferences ( PMIDs )
9VKETPLHSSSSTSLSdbPTM 3.0;PhosphoGRID 2.0;curated17563356; 16381945; 23193290; 20702584; 22817900; 19823750;
10KETPLHSSSSTSLSSPhosphoGRID 2.0;PhosphoPep 2.0;curated20702584; 19060867; 26040406
11ETPLHSSSSTSLSSLdbPTM 3.0;PhosphoGRID 2.0;curated17563356; 16381945; 23193290; 22369663; 22817900; 24961812;
12TPLHSSSSTSLSSLFdbPTM 3.0;curated17563356; 16381945; 23193290; 22369663; 22817900; 20377248
13PLHSSSSTSLSSLFRPhosphoGRID 2.0;PhosphoPep 2.0;curated19779198; 19060867; 24961812; 20377248
14LHSSSSTSLSSLFRPdbPTM 3.0;curated17563356; 16381945; 23193290; 22369663; 22817900; 24961812;
17SSSTSLSSLFRPTKLcurated24961812
28PTKLKNLSAKIFNGGPHOSIDA;curated21081558; 22817900; 19795423
39FNGGGNQSYSKTDDVcurated22369663
58SRSSKKNTDSDQEDQdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated17563356; 18407956; 16381945; 23193290; 21126336; 19366988;
60SSKKNTDSDQEDQIKdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17563356; 18407956; 16381945; 23193290; 21177495; 20702584;
81RRSTIGKSPQGNGALdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated17563356; 18407956; 16381945; 23193290; 20489023; 19060867;
98ESHVVASSTLTGISPcurated22817900; 19547744
104SSTLTGISPTSAKKAdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 20489023; 19060867; 19366988;
106TLTGISPTSAKKAPIdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.018407956; 16381945; 23193290; 20489023; 19366988
107LTGISPTSAKKAPIDPhosphoGRID 2.020489023
115AKKAPIDYSPSRPLPcurated25315811
116KKAPIDYSPSRPLPNPhosphoPep 2.019060867
164HHPHPVRSTAHSNIScurated22817900; 19547744
168PVRSTAHSNISTVSScurated25315811
Sequence
(Fasta)		MVKETPLHSS SSTSLSSLFR PTKLKNLSAK IFNGGGNQSY SKTDDVSRSS SRSSKKNTDS 60
DQEDQIKYNK PNDRRSTIGK SPQGNGALSK ESHVVASSTL TGISPTSAKK APIDYSPSRP 120
LPNNHNPVRT GHTVPHLPHS IHNPINYIHQ GSKDAFHHPH PVRSTAHSNI STVSSAKSDT 180
PSSNLSYQAH MHPVEILQKQ IEDKHFMDSQ ASTPGSVELQ HNSSSGSDDT SSRKKKSLRL 240
TRFFKKIHND YHDNHHHHHH HNRGSTPTKP KLNLNTNENI VESNGKALYE TDNPVELLEK 300
YGIPGRKLGE GASGSVSVVE RTDGKLFACK MFRKPHLNNE GTNQSQLANY SKKVTTEFCI 360
GSTLHHENIV ETLDMLTEGD TYLLVMEYAP YDFFNLVMSN LMTQDEVNCY FKQLCHGVNY 420
LHSMGLAHRD LKLDNCVVTK DGILKLIDFG SAVVFQYPYE DTIVKSHGIV GSDPYLAPEL 480
LKQTSYDPRV ADVWSIAIIF YCMVLKRFPW KAPKKSFNSF RLFTEEPEDE DDIVRGPNKI 540
LRLLPRHSRT IIGRMLALEP KQRVLMNDVV KDDWLVSVPS CEVDPTSGDL VEKPKNHKHH 600
LVTEEELNEL TKQHGNKDSN 621
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
Pfam

PF00069--Pkinase
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004672--F:protein kinase activity
GO:0004674--F:protein serine/threonine kinase activity
GO:0035556--P:intracellular signal transduction
GO:0006468--P:protein phosphorylation