| Tag |
Content |
| dbPAF ID |
dbPAF-0016483 |
| Uniprot Accession |
Q12099; FAL1_YEAST; D6VS07;
|
| Genbank Protein ID |
NP_010304.3;
|
| Genbank Nucleotide ID |
NM_001180329.3;
|
| Protein Name |
ATP-dependent RNA helicase FAL1 |
| Protein Synonyms/Alias |
Translation initiation factor four A-like protein 1; |
| Gene Name |
FAL1 |
| Gene Synonyms/Alias |
YDR021W;PZC399;YD9335.07; |
| Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID |
559292 |
Functional Description
(View all) |
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.Functional Description
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA. |
Phosphorylation Sites
|
dbPAF PTMs: 3 |
Sequence
(Fasta) | MSFDREEDQK LKFKTSKKLK VSSTFESMNL KDDLLRGIYS YGFEAPSSIQ SRAITQIISG 60
KDVIAQAQSG TGKTATFTIG LLQAIDLRKK DLQALILSPT RELASQIGQV VKNLGDYMNV 120
NAFAITGGKT LKDDLKKMQK HGCQAVSGTP GRVLDMIKKQ MLQTRNVQML VLDEADELLS 180
ETLGFKQQIY DIFAKLPKNC QVVVVSATMN KDILEVTRKF MNDPVKILVK RDEISLEGIK 240
QYVVNVDKEE WKFDTLCDIY DSLTITQCVI FCNTKKKVDW LSQRLIQSNF AVVSMHGDMK 300
QEERDKVMND FRTGHSRVLI STDVWARGID VQQVSLVINY DLPEIIENYI HRIGRSGRFG 360
RKGVAINFIT KADLAKLREI EKFYSIKINP MPANFAELS
Fasta Sequence
>Q12099|FAL1|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
MSFDREEDQKLKFKTSKKLKVSSTFESMNLKDDLLRGIYSYGFEAPSSIQSRAITQIISGKDVIAQAQSGTGKTATFTIGLLQAIDLRKKDLQALILSPTRELASQIGQVVKNLGDYMNVNAFAITGGKTLKDDLKKMQKHGCQAVSGTPGRVLDMIKKQMLQTRNVQMLVLDEADELLSETLGFKQQIYDIFAKLPKNCQVVVVSATMNKDILEVTRKFMNDPVKILVKRDEISLEGIKQYVVNVDKEEWKFDTLCDIYDSLTITQCVIFCNTKKKVDWLSQRLIQSNFAVVSMHGDMKQEERDKVMNDFRTGHSRVLISTDVWARGIDVQQVSLVINYDLPEIIENYIHRIGRSGRFGRKGVAINFITKADLAKLREIEKFYSIKINPMPANFAELS
|
| Keyword |
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0347--Helicase
KW-0378--Hydrolase
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0690--Ribosome biogenesis
KW-0694--RNA-binding
KW-0698--rRNA processing
|
| Interpro |
IPR011545--DEAD/DEAH_box_helicase_dom
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000629--RNA-helicase_DEAD-box_CS
IPR014014--RNA_helicase_DEAD_Q_motif
|
| PROSITE |
PS00039--DEAD_ATP_HELICASE
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51195--Q_MOTIF
|
| Pfam |
PF00270--DEAD
PF00271--Helicase_C
|
| Gene Ontology |
GO:0071013--C:catalytic step 2 spliceosome
GO:0097078--C:FAL1-SGD1 complex
GO:0005730--C:nucleolus
GO:0030688--C:preribosome, small subunit precursor
GO:0005524--F:ATP binding
GO:0004004--F:ATP-dependent RNA helicase activity
GO:0003723--F:RNA binding
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5
8S rRNA, L--U-rRNA)
GO:0010468--P:regulation of gene expression
GO:0010501--P:RNA secondary structure unwinding
GO:0008380--P:RNA splicing
|
