dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016477
Uniprot Accession Q12090; REXO3_YEAST; D6VYA7; Q7LI70;
Genbank Protein ID NP_013208.1;
Genbank Nucleotide ID NM_001181994.1;
Protein Name RNA exonuclease 3
Protein Synonyms/Alias
Gene Name REX3
Gene Synonyms/Alias YLR107W;L2904;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
3' to 5' exoribonuclease required for proper 3' end maturation of MRP RNA and of the U5L snRNA.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
60EVHVAKNSLSGQSYKcurated23825934
Sequence
(Fasta)
MGSLLRPVDL VNQPLGFQER YKILQKLFKQ LQKAYAHTKG TNIDLERLAT RLEVHVAKNS 60
LSGQSYKFNM SILLRDVLKY KGDLSKIKIN GRPLKGAKPH LSSIGNANSI TTKSKAMEAL 120
KALILDSKVL EKNGYIVKEM QNKTNDDNST QLYAPCLRCS SNFKKTDIME KTLCRYHPLK 180
RIYNRDTKNH QYPCCGETTD SVSFLRLGCK TFFHHVFRGE SYDELCKISK FSSTDDIDGV 240
ENVLSLDCEM AFTSLGYEMI RLTIVDFFTG KTLFDHVIQP IGDIVDLNSD FSGVHEIDRT 300
NCPTYKEALD VFLSENLINK NSILIGHGLE NDLNVMRLFH NKVIDTAILY SRTKFKVSLK 360
NLAFEVLSRK IQNGEHDSSQ DAIATMDVVK VKIGISPSQN KWEK 405
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0269--Exonuclease
KW-0378--Hydrolase
KW-0540--Nuclease
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0698--rRNA processing

Interpro

IPR013520--Exonuclease_RNaseT/DNA_pol3
IPR012337--RNaseH-like_dom

PROSITE
Pfam
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0008408--F:3'-5' exonuclease activity
GO:0000175--F:3'-5'-exoribonuclease activity
GO:0003676--F:nucleic acid binding
GO:0000467--P:exonucleolytic trimming to generate mature 3'-end of 5
8S rRNA fr--m tricistronic rRNA transcript (SSU-rRNA, 5
8S rRNA, L--U-rRNA)
GO:0043628--P:ncRNA 3'-end processing
GO:0034476--P:U5 snRNA 3'-end processing