dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016403
Uniprot Accession Q10951; BYR4_SCHPO;
Genbank Protein ID NP_593149.1;
Genbank Nucleotide ID NM_001018546.2;
Protein Name Protein byr4
Protein Synonyms/Alias
Gene Name byr4
Gene Synonyms/Alias SPAC222.10c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Has an essential role in ensuring cytokinesis and septation occur only once during mitosis. It does so by interacting with the ras1 signaling pathways, thereby suppressing them.
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
326KASSKHSSPVKGNSSdbPTM 3.0;UniProt18257517; 16381945; 23193290
499TLIQNLNSPRTPKIVdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
533RDFDTPISPSRPALIdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MTEVECWDDD PDFASDVDNA SLFTQSIATT SASTSVDDGF SFDDSISRLN SLSISDVPSA 60
HSRVEQWNQQ VHNLNHELSS NKNRISSNVE GYEDDFSFDE EGEEGNNEFN TLRPNKYQDA 120
DVDEFNTIRA SETASQRPPI PFSSDTLKKT YLSSENDARY PSVSDSPYCE SEGFSSFEDD 180
FEIDPDTDLN SILHRKQNRM DPKASFSSVE QSSLRTPSSA HNDDGFWDDF DIDFNNETES 240
IFRKKIRSPN TINQKHPYIS STISYQPNVH QDAKYYPLCK DIFPSLANEN PHSDNPNLKY 300
SSKTLSKRDT SSHYPETLKA SSKHSSPVKG NSSISSTWTP SNLKIYHSKN SMGLMDLDAL 360
KTVASNSKYR TKPKNCKTYG DGTELDTLDE LPVDYEFELK LRKKQTTKVS GTPKSKHAGS 420
TQEWHSHTTP RSTSKHENNL NNITNSAKNE HIRSQRQHKT HAAPSKELTK ESLSNDQLSV 480
KEKRRHHKKA PTLIQNLNSP RTPKIVGKMR YNPTKHCWEG NDYAIRDFDT PISPSRPALI 540
SNISTKKGIQ VVGNMVYDPT RLRWIDNSIS GQEAEDPFSG FDDLEDTDST SQYLNENSGS 600
FNGSINSIIN FPDMSEIYDV GPEFEKKQFS EDIQWRKRID GWFFSFKNDD RSRLWELYNI 660
LNAEQ 666
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0472--Membrane
KW-0498--Mitosis
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro
PROSITE
Pfam
Gene Ontology

GO:0005829--C:cytosol
GO:0044732--C:mitotic spindle pole body
GO:0005886--C:plasma membrane
GO:0005096--F:GTPase activator activity
GO:0051301--P:cell division
GO:0007067--P:mitotic nuclear division
GO:0031030--P:negative regulation of septation initiation signaling
GO:0043547--P:positive regulation of GTPase activity
GO:0046578--P:regulation of Ras protein signal transduction