dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016369
Uniprot Accession Q10488; ETR1_SCHPO;
Genbank Protein ID NP_594891.1;
Genbank Nucleotide ID NM_001020320.2;
Protein Name Probable trans-2-enoyl-CoA reductase, mitochondrial
Protein Synonyms/Alias
Gene Name etr1
Gene Synonyms/Alias SPAC26F1.04c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Oxidoreductase with a preference for short and medium chain substrates, including trans-2-hexenoyl-CoA (C6), trans-2-decenoyl-CoA (C10), and trans-2-hexadecenoyl-CoA (C16). May play a role in mitochondrial fatty acid synthesis (By similarity).
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
40KEVLRAVSYNVPKCScurated22817900
Sequence
(Fasta)
MSFFKTAVRR FSSTSITRGM AKAIAYSEYG NPKEVLRAVS YNVPKCSKNQ VNVRFLASPI 60
NPSDINQIQG VYPSKPPFTN DVCSSKPSAV AGNEGLVEVV DVGDQFKGTF SPGQWAILGS 120
VNLGSWRTEM NIDGRSLVPV DKSAFPSIAE AATLSVNPCT AYCLLQHVVQ LNKGDWFIQD 180
GANSMVGIAT IQLAKHFGYK SINVVRNRPD IEKLKEQLKS LGATIVITDE ELMDRKTMKQ 240
KVPEWIQGGE VKLGIDCVSG RVAAEMAKYM SKGATMATFG GMSRQPLPVP VSLLIFKNLK 300
FHGFWVTKWK SEHPEEFLKI IHKVEDFYRN GTLKTVNTEL VSLKEDADEK TFLDTFLNAI 360
EGHGKKIIKF EH 373
Keyword

KW-0181--Complete proteome
KW-0275--Fatty acid biosynthesis
KW-0276--Fatty acid metabolism
KW-0444--Lipid biosynthesis
KW-0443--Lipid metabolism
KW-0496--Mitochondrion
KW-0521--NADP
KW-0560--Oxidoreductase
KW-1185--Reference proteome
KW-0809--Transit peptide

Interpro

IPR013149--ADH_C
IPR002085--ADH_SF_Zn-type
IPR011032--GroES-like
IPR016040--NAD(P)-bd_dom

PROSITE
Pfam

PF00107--ADH_zinc_N

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005759--C:mitochondrial matrix
GO:0005739--C:mitochondrion
GO:0016631--F:enoyl-[acyl-carrier-protein] reductase activity
GO:0019166--F:trans-2-enoyl-CoA reductase (NADPH) activity
GO:0008270--F:zinc ion binding
GO:0006633--P:fatty acid biosynthetic process