dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016366
Uniprot Accession Q10475; IF4G_SCHPO; P78832;
Genbank Protein ID NP_594602.1;
Genbank Nucleotide ID NM_001020030.2;
Protein Name Eukaryotic translation initiation factor 4 gamma
Protein Synonyms/Alias
Gene Name tif471
Gene Synonyms/Alias SPAC17C9.03;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.
Phosphorylation Sites
 dbPAF PTMs: 22 (View all)
PositionPeptidesSourceReferences ( PMIDs )
81DTEKYNSSKSPVNKEcurated22817900
83EKYNSSKSPVNKEGSdbPTM 3.0;UniProt18257517; 16381945; 23193290
452VSDQVVESPNSSTLSdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
455QVVESPNSSTLSPRNdbPTM 3.0;UniProt18257517; 16381945; 23193290
456VVESPNSSTLSPRNGdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
459SPNSSTLSPRNGFAPdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
505PNPSETNSRAETPTAcurated22817900
509ETNSRAETPTAAPPQcurated22817900
518TAAPPQISEEEASQRcurated22817900
866ASAFSDKSSRGMYSSdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
880SSRQSSRSGSNTHSHcurated22817900
882RQSSRSGSNTHSHAGdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
884SSRSGSNTHSHAGPGdbPTM 3.0;UniProt18257517; 16381945; 23193290
886RSGSNTHSHAGPGFGdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
911LGIDRGFSSSGAGFGdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
913IDRGFSSSGAGFGSGcurated22817900
919SSGAGFGSGSNYKSAdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
921GAGFGSGSNYKSAPSdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
923GFGSGSNYKSAPSRGdbPTM 3.0;UniProt18257517; 16381945; 23193290
1300SRMGGRGSNPPFSSSdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)		MSSKPPSNTP KFSYARALAS SQSNKSNSTK ASENNTATAE KQAVKPSGVE PTNTSRANAQ 60
KKTESTGKIT SEADTEKYNS SKSPVNKEGS VEKKSSEKSS TNNKPWRGDN TSKPSANSSA 120
ERTSSQHQKP ETSSQIGKDN AAPVENVNEK STSQETAPPV STVPIQFGSI TRNAAIPSKP 180
KVSGNMQNKS GVSSYSSKSQ SVNSSVTSNP PHTEEPVAAK PEASSTATKG PRPTTSASNT 240
NTSPANGAPT NKPSTDINTT DPATQTTQVS ASNSPALSGS STPSNTSSRS NRQNHGNFSE 300
KRHYDRYGNS HPSYNKYSHY QHGFNYNNSG NNRNESGHPR FRNSRRNYNN QGAYPTYMSN 360
GRSANQSPRN NPQNVNNGST PIQIPVSLQT PYGQVYGQPQ YIVDPNMVQY GPILQPGYVP 420
QYYPVYHQTP YTQNFPNMSR SGSQVSDQVV ESPNSSTLSP RNGFAPIVKQ QKKSSALKIV 480
NPVTHTEVVV PQKNASSPNP SETNSRAETP TAAPPQISEE EASQRKDAIK LAIQQRIQEK 540
AEAEAKRKAE EKARLEAEEN AKREAEEQAK REAEEKAKRE AEEKAKREAE EKAKREAEEN 600
AKREAEEKAK REAEEKAKRE AEEKAKREAE EKAKREAEEK AKREAEEKAK REAEEKAKRE 660
AEENAKREAE EKAKREAEEN AKREAEEKVK RETEENAKRK AEEEGKREAD KNPEIKSSAP 720
LASSEANVDT SKQTNATEPE VVDKTKVEKL KASEGKSTSS LSSPSHSTSS KRDLLSGLES 780
LSLKTNPKSE QCLESLLNSQ FITDFSALVY PSTIKPPSTE EALKAGKYEY DVPFLLQFQS 840
VYTDKPMKGW DERMKETVAS AFSDKSSRGM YSSSRQSSRS GSNTHSHAGP GFGGPSERKG 900
ISRLGIDRGF SSSGAGFGSG SNYKSAPSRG VSHHGHGGMS GSHRGSQRGS RRGGGERDKP 960
DPSSLTIPVD QVAPLQLSAN RWQPKKLTEK PAETKGEDEE ALLPPEVVQR KVKGSLNKMT 1020
LEKFDKISDQ ILEIAMQSRK ENDGRTLKQV IQLTFEKATD EPNFSNMYAR FARKMMDSID 1080
DSIRDEGVLD KNNQPVRGGL LFRKYLLSRC QEDFERGWKA NLPSGKAGEA EIMSDEYYVA 1140
AAIKRRGLGL VRFIGELFKL SMLSEKIMHE CIKRLLGNVT DPEEEEIESL CRLLMTVGVN 1200
IDATEKGHAA MDVYVLRMET ITKIPNLPSR IKFMLMDVMD SRKNGWAVKN EVEKGPKTIA 1260
EIHEEAERKK ALAESQRPSS GRMHGRDMNR GDSRMGGRGS NPPFSSSDWS NNKDGYARLG 1320
QGIRGLKSGT QGSHGPTSLS SMLKGGSVSR TPSRQNSALR REQSVRAPPS NVAVTSANSF 1380
ELLEEHDHDN DGGQKDSNSK TSS 1404
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0597--Phosphoprotein
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0694--RNA-binding
Interpro

IPR016024--ARM-type_fold
IPR022745--eIF4G1_eIF4E-bd
IPR016021--MIF4-like
IPR003890--MIF4G-like_typ-3
PROSITE
Pfam

PF12152--eIF_4G1
PF02854--MIF4G
Gene Ontology

GO:0010494--C:cytoplasmic stress granule
GO:0005829--C:cytosol
GO:0016281--C:eukaryotic translation initiation factor 4F complex
GO:0048471--C:perinuclear region of cytoplasm
GO:0005198--F:structural molecule activity
GO:0003743--F:translation initiation factor activity
GO:0002183--P:cytoplasmic translational initiation
GO:0042273--P:ribosomal large subunit biogenesis