dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016360
Uniprot Accession Q10452; GSK3_SCHPO; O94456;
Genbank Protein ID NP_593134.1;
Genbank Nucleotide ID NM_001018530.2;
Protein Name Protein kinase gsk3
Protein Synonyms/Alias Protein kinase skp1;
Gene Name gsk3
Gene Synonyms/Alias skp1;SPAC1687.15;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Interacts with cdc14 which is thought to play a role in the initiation and completion of mitosis. Involved in the positive regulation of mis12.
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
191VAGEPNVSYICSRYYdbPTM 3.0;UniProt18257517; 16381945; 23193290
192AGEPNVSYICSRYYRdbPTM 3.0;SysPTM 2.0;curated8524294; 18257517; 16381945; 23193290; 19366988; 22817900
335NSRNPDASPRHLPELdbPTM 3.0;UniProt8524294; 16381945; 23193290
Sequence
(Fasta)
MNHGTKIPVD PFRIIKETAR DGSTGEVKQL SYTSSKVVGS GSFGVVMQVH LIESDSKAAI 60
KRVLQDKRFK NRELQIMRIM KHPNIVDLIA YYYTTGDNSD EVYLNLVLEF MPETIYRASR 120
LYTRQKLSMP MLEVKLYIYQ LLRSLAYIHA SGICHRDIKP QNLLLDPENG ILKLCDFGSA 180
KILVAGEPNV SYICSRYYRA PELIFGATDY THAIDIWSTG CVMAELMLGH PLFPGESGID 240
QLVEIIKILG TPSREQIKTM NPNYMEHRFP QIRPQPLSRV FSRSVPLDAL DLLSKMLQYT 300
PTDRLTAAEA MCHPFFDELR DPNTKLHNSR NPDASPRHLP ELFNFSPFEL SIRPDLNQKL 360
IPSHARDALP VKLDDFVPIP IHRARID 388
Keyword

KW-0067--ATP-binding
KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0418--Kinase
KW-0498--Mitosis
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004672--F:protein kinase activity
GO:0004674--F:protein serine/threonine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0004713--F:protein tyrosine kinase activity
GO:0051301--P:cell division
GO:0007067--P:mitotic nuclear division
GO:0018105--P:peptidyl-serine phosphorylation
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0018108--P:peptidyl-tyrosine phosphorylation
GO:0051984--P:positive regulation of chromosome segregation
GO:0006468--P:protein phosphorylation
GO:0033047--P:regulation of mitotic sister chromatid segregation
GO:0007165--P:signal transduction