dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0016355 | ||||||||
| Uniprot Accession | Q10432; CCQ1_SCHPO; | ||||||||
| Genbank Protein ID | NP_588210.1; | ||||||||
| Genbank Nucleotide ID | NM_001023200.2; | ||||||||
| Protein Name | Coiled-coil quantitatively-enriched protein 1 | ||||||||
| Protein Synonyms/Alias | Structural maintenance of chromosomes protein ccq1;SMC protein ccq1; | ||||||||
| Gene Name | ccq1 | ||||||||
| Gene Synonyms/Alias | SPCC188.07; | ||||||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) | ||||||||
| NCBI Taxa ID | 284812 | ||||||||
| Functional Description (View all) |
Component of the meiotic bouquet that facilitates meiotic nuclear reorganization of the telomeres to the centrosome. Links telomeres to the meiotic centrosome component pcp1. Essential for the formation of normal telomere clusters during meiotic prophase. Required for telomere length regulation and chromosome segregation. Required for proper positioning of nucleosomes at heterochromatic loci and for transcriptional gene silencing (TGS) function of the Snf2/Hdac-containing repressor complex (SHREC). | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MSEINDFTNS IIINESDTKY EVYSEVNSSN RWIAKEDCPS PLEDVWLLKL AGHKRKLEEP 60 LSCMRNEEPA SKQREIEKFL RTDLDHSEND FLTQEVDEFP STQQLFPIPL QNDTAFDSSE 120 ESITKSSKSS FSVLDIGLPM SALQRKMMHR LVQYFAFCID HFCTGPSDSR IQEKIRLFIQ 180 SAHNIAKHPS LYDTEVRNPS AAESTNSHVS LDASNFSSYA ENSSKFLFLQ ELFKNLSPSY 240 SKTFFLFISN QFLANTLTQW LKSQNIDAEL WAEEDAKTSQ HPAIWICVSK KAPSASHFLQ 300 SCPDLSATIF YDIEAYMSVT SSLPSIQSLV LRLIHLGSIE HAIKCFQSSY NASFLVNIVG 360 VVATLSSSSE ENSEASNLST LFEKSGNFEE ILGSESHSSI TEKTRDIAKN VATWLKNGEN 420 FSSWPLPPLM DLASLSVAEP RDSQPSVSQV NDTFVKSSDS TFPSSQSMQS PSKLHSLTSN 480 ATDLLSSSSL KKNFFSQQEA DEVELSNNYD LQGAAVQYLQ RRLRMVEDEL HEAINSKNVQ 540 QSRSEELEQQ ISKLTDNLQE YRNTVRELKL DLEKSKKKNE DLSKLEVEKV EEIANLKKEL 600 THLAKQQEFG FKYVQEFSNE DLQGKLIEAN EKNYKLTQLL KTQKEDADFI TNQYQNASTF 660 AAEQSKEVAK LQAECKRLQA INSKVMEEVK VYNDSRVEAL LAKVSSLEET LKILEQKSLP 720 KFTPHNQSPR IIDSN 736 |
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| Keyword | KW-0158--Chromosome |
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| Interpro | IPR021006--HDA_complex_subunit-2/3 |
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| PROSITE | |||||||||
| Pfam | PF11496--HDA2-3 |
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| Gene Ontology | GO:0035974--C:meiotic spindle pole body |