dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016354
Uniprot Accession Q10428; 2AD1_SCHPO;
Genbank Protein ID NP_588206.1;
Genbank Nucleotide ID NM_001023196.2;
Protein Name Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta 1 isoform
Protein Synonyms/Alias PP2A, B subunit, B' delta 1 isoform;
Gene Name par1
Gene Synonyms/Alias pbp1;SPCC188.02;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Has a role in cell shape control and septum formation.
Phosphorylation Sites
dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
94TVRKQRSSLYHISENcurated22817900
96RKQRSSLYHISENRNdbPTM 3.0;UniProt18257517; 16381945; 23193290
99RSSLYHISENRNLVRdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
109RNLVRLPSFTDVPVNdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
542TERLKKLSLDYTNG-dbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MKGIKSKMLS RGKSQDTQKS SKKKESKKSN SHDSSKAPKE SPSTDPNGSV IGAQNDFLTV 60
PKHSGKKVPI DTTPTPRDEI LLENVRTVRK QRSSLYHISE NRNLVRLPSF TDVPVNKWHS 120
LALEKLEQCC VVFDFNDPST DLYGKEVKRE ALQDLIDLIS VRKEAIDESL YPSIVHMFAV 180
NVFRPLPPPS NPPGEIMDLE EDEPALEVAW PHLHLVYDFF LRFFESPSLN TSVAKVYINQ 240
KFIRKLLVLF DSEDPRERDF LKTTLHRIYG KFLSLRAFIR RSINNLFLQF VYENEQFNGI 300
AELLEILGSI INGFALPLKE EHKIFLSRVL IPLHKAKSLP LYYPQIAYGI VQFVEKDSSV 360
TEEVVLGLLR YWPKVNSSKE VLFLNEIEDI IEVMEPSEFL KIQVPLFHKL ATSISSQNFQ 420
VAERALYFFN NDYFVHLVEE NVDIILPIIY PALFEISKSH WNRVIHSMVC NVLKLFMDIN 480
PSLFDEVDAE YSESRRKKED EEIIREERWT ILENIAKENA MKLKSQNPTT VHSTTERLKK 540
LSLDYTNG 549
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR002554--PP2A_B56

PROSITE
Pfam

PF01603--B56

Gene Ontology

GO:0005826--C:actomyosin contractile ring
GO:0032153--C:cell division site
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0044732--C:mitotic spindle pole body
GO:0005634--C:nucleus
GO:0000159--C:protein phosphatase type 2A complex
GO:0005816--C:spindle pole body
GO:0008601--F:protein phosphatase type 2A regulator activity
GO:0031030--P:negative regulation of septation initiation signaling
GO:0031029--P:regulation of septation initiation signaling
GO:0007165--P:signal transduction