| Tag |
Content |
| dbPAF ID |
dbPAF-0016353 |
| Uniprot Accession |
Q10425; EIF3B_SCHPO;
|
| Genbank Protein ID |
NP_594528.1;
|
| Genbank Nucleotide ID |
NM_001019957.2;
|
| Protein Name |
Eukaryotic translation initiation factor 3 subunit B |
| Protein Synonyms/Alias |
|
| Gene Name |
SPAC25G10.08 |
| Gene Synonyms/Alias |
|
| Organism |
Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID |
284812 |
Functional Description
(View all) |
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.Functional Description
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. |
Phosphorylation Sites
|
dbPAF PTMs: 4 |
Sequence
(Fasta) | MSEILIEEIK DQIVVKDEEI DVSELEVKLN VTKPVGYDTV VVIEGAPVVE EAKQQDFFRF 60
LSSKVLAKIG KVKENGFYMP FEEKNGKKMS LGLVFADFEN VDGADLCVQE LDGKQILKNH 120
TFVVRKLNQL EKAFSTPDEF SFEEREFKER EHLRSWLTDY YGRDQFISYY GNRVSVNWNR 180
KSDVPEQIVD RENWTETYVQ WSPMGTYLVS LHLRGIQLWG GESWGMCARF LHPYVKFVDF 240
SPNEKYLVSW SYEPVRLPPI GHPARETMPF TDDDEGKHCF VWDIASGRIL RSFKIPPQPE 300
GSKDGKKVIW PIFKWSADDK YLARVTVGQS ISVYETPSLA LVDKKTIKID GVQNFEWCPV 360
SDALGRDSKE QLLAYWTPEI TNQPARVALI SIPSKSTIRT KNLFNVSDCK LYWQSNGDYL 420
CVKVDRHTKT KKSTFSNLEI FRIREKNIPV EVVDLKDVVL NFAWEPKSDR FAIISANDQV 480
LNSTNVKTNL SFYGFEQKKN TPSTFRHIIT FDKKTCNSLF MAPKGRFMVA ATLGSSTQYD 540
LEFYDLDFDT EKKEPDALAN VQQIGSAEHF GMTELEWDPS GRYVTTSSTI WRHKLENGYR 600
LCDFRGTLLR EEMIGEFKQF IWRPRPPSPL TKEDMKKIRK KLKDYNRLFD EEDIAEQSSA 660
NRELAARRRQ LISEWQKYRD EVIARVAEER AITGQPAITV PAEEEEIIQE TVEEVISEEI 720
EPVED
726Fasta Sequence
>Q10425|SPAC25G10.08|Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
MSEILIEEIKDQIVVKDEEIDVSELEVKLNVTKPVGYDTVVVIEGAPVVEEAKQQDFFRFLSSKVLAKIGKVKENGFYMPFEEKNGKKMSLGLVFADFENVDGADLCVQELDGKQILKNHTFVVRKLNQLEKAFSTPDEFSFEEREFKEREHLRSWLTDYYGRDQFISYYGNRVSVNWNRKSDVPEQIVDRENWTETYVQWSPMGTYLVSLHLRGIQLWGGESWGMCARFLHPYVKFVDFSPNEKYLVSWSYEPVRLPPIGHPARETMPFTDDDEGKHCFVWDIASGRILRSFKIPPQPEGSKDGKKVIWPIFKWSADDKYLARVTVGQSISVYETPSLALVDKKTIKIDGVQNFEWCPVSDALGRDSKEQLLAYWTPEITNQPARVALISIPSKSTIRTKNLFNVSDCKLYWQSNGDYLCVKVDRHTKTKKSTFSNLEIFRIREKNIPVEVVDLKDVVLNFAWEPKSDRFAIISANDQVLNSTNVKTNLSFYGFEQKKNTPSTFRHIITFDKKTCNSLFMAPKGRFMVAATLGSSTQYDLEFYDLDFDTEKKEPDALANVQQIGSAEHFGMTELEWDPSGRYVTTSSTIWRHKLENGYRLCDFRGTLLREEMIGEFKQFIWRPRPPSPLTKEDMKKIRKKLKDYNRLFDEEDIAEQSSANRELAARRRQLISEWQKYRDEVIARVAEERAITGQPAITVPAEEEEIIQETVEEVISEEIEPVED
|
| Keyword |
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0597--Phosphoprotein
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0694--RNA-binding
KW-0853--WD repeat
|
| Interpro |
IPR011042--6-blade_b-propeller_TolB-like
IPR011400--EIF3B
IPR000504--RRM_dom
IPR003954--RRM_dom_euk
IPR013979--TIF_beta_prop-like
IPR015943--WD40/YVTN_repeat-like_dom
|
| PROSITE |
PS50102--RRM
|
| Pfam |
PF08662--eIF2A
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0071540--C:eukaryotic translation initiation factor 3 complex, eIF3e
GO:0071541--C:eukaryotic translation initiation factor 3 complex, eIF3m
GO:0003743--F:translation initiation factor activity
GO:0002183--P:cytoplasmic translational initiation
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation
GO:0006413--P:translational initiation
|
