dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0016344 |
| Uniprot Accession | Q10366; PIK1_SCHPO; |
| Genbank Protein ID | NP_594842.1; |
| Genbank Nucleotide ID | NM_001020271.2; |
| Protein Name | Phosphatidylinositol 4-kinase pik1 |
| Protein Synonyms/Alias | |
| Gene Name | pik1 |
| Gene Synonyms/Alias | SPAC22E12.16c; |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID | 284812 |
| Functional Description (View all) |
Acts on phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol 1,4,5,-trisphosphate. PIK1 is part of a nuclear phosphoinositide cycle and could control cytokinesis through the actin cytoskeleton (By similarity). |
| Phosphorylation Sites |
dbPAF PTMs: 5 |
| Sequence (Fasta) | MPSSNSGNEL LLRFFESAHF TSQLCVAYLS RYPNNIGIHH FLCEKLATFP YEEIEFFIPQ 60 LIHLVLNKDS ESVALEEFII SQCEQNTQCA LITFWYLQAH MVDLGLQPHS SCFKICKRLY 120 NRIQILVFMS SSSLIQSQQK ISENVTPALI LSGIMLGGVC VPELLKKAGP IAIAQGRKAP 180 RQDPDESDVD VLRRLSTEPR YSLDVLRSSL NNSIVEQHSE VSLRLKAPEL TRTHSYQSSA 240 TLSIDEQRRV LRSNYFQQEI QFLFALQDIS IRLIIVPRQA RLSSLRAELA LLNNNLPADV 300 NIPLLRSYHK EVSHKIVRID PKEATILNSA ERVPYLIMVE VLSGELSFEP QSKKNKAKVQ 360 KIVSHKNQRK RWFDLTDVDP YTNLQDSTDN DISESESEGG DLSMSPLIKG LVPDTLSLSK 420 SFSSFGNVSL QVPSSHRDTD VVLLSGRHSD SDGNGALKRS KIYASEITAR MRAAATMLSQ 480 LDAEGSRRPK AETERIKNSI ILDMQRLEEE RLNEPSIYPV SVDISCAEDL RFGKETQKAE 540 RKGDRDDPSA ATFQEDWYAK KERIRKSSPY GHYPNWDLVS VIVKTGADLR QETFACQLIY 600 AFQRVWLECK EKVWVRRMKI LVTGDNSGLI ETITNAISVH SIKKNLTKQL REAELAQGKI 660 AGKNVVTLKD YFIKQFGDPN SSRYRQAQTN FLQSLVAYSI ISYLLQLKDR HNGNVLIDSE 720 GHIIHIDFGF LLTNTPGNVG FESAPFKLTA DYLEILDDRF DEYRSLMKAA FKSVRKNADQ 780 IILLVEVMQN NSTMPCFRAG ENTSAQLLQR FQLQLGDKEC DDFVDLLIQK ANCSVWTRLY 840 DLFQNITNGI Y 852 |
| Keyword | KW-0181--Complete proteome |
| Interpro | IPR016024--ARM-type_fold |
| PROSITE | PS00915--PI3_4_KINASE_1 |
| Pfam | |
| Gene Ontology | GO:0005737--C:cytoplasm |