dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016343
Uniprot Accession Q10364; SCK2_SCHPO;
Genbank Protein ID NP_594840.1;
Genbank Nucleotide ID NM_001020269.2;
Protein Name Serine/threonine-protein kinase sck2
Protein Synonyms/Alias
Gene Name sck2
Gene Synonyms/Alias SPAC22E12.14c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Protein kinase that is part of growth control pathway which is at least partially redundant with the cAMP pathway.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
78STVGNRNSNDILPEVcurated22817900
Sequence
(Fasta)
MMNKWAKNWF GLSKKSVSTN SAKGSLPRSP LASIQTNQPV EEGEGGSLPS VSNLGPSSID 60
HPMEEFASDQ STVGNRNSND ILPEVDHEPS GYLKLQIGSL VLGGPHTDAA LAMECSRLNQ 120
LFVVVQFGTT EFVSPPLKWE SPGRDIGTSS RDSANVSRSS SMMSSHPIPT PAIQRTSSIP 180
NPLTPSYVVF DVAKPVPIDV NIYDHGNNNE FVGRTYIHPS YNYGQFEQFC NSVEVSPAYN 240
RMVDLRLSLN TVFQPLSQHS YGPDDFVPLK LIGKGTFGQV YLVRKKDTER VYAMKVLSKK 300
VIVRRKEVAH TVGERDILVQ TSAADSPFIV ALRFSFQTPK DLYLVTDYMA GGELFWHLQK 360
SVRFPEERAK FYIAELLLAL QALHKRGIVY RDLKPENILL DVQGHIALCD FGLSKANLSV 420
GTTTRTFCGT TDYLAPEVIL DEAGYDMMVD FWSLGVLLYE MTCGWSPFYA DNTQQLYKNI 480
VFGKVRFPRG LLSVEARDLI KLLLNRNPKH RLGAHGDVEE VMKHPFFDGI DWKKLAAKEI 540
SPPFKPIVEG EIDVSNFDVE FTNKAIDRDF SSTDEMSTSA PLSSTVQNGF KGFTYIDASA 600
MDEAFGYHNS NDSASSISSQ DDYSKDNSDM DLNRANDEVF MGQIDP 647
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR000961--AGC-kinase_C
IPR011009--Kinase-like_dom
IPR017892--Pkinase_C
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS51285--AGC_KINASE_CTER
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase
PF00433--Pkinase_C

Gene Ontology

GO:0005829--C:cytosol
GO:0005635--C:nuclear envelope
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0035556--P:intracellular signal transduction
GO:0031138--P:negative regulation of conjugation with cellular fusion
GO:1901644--P:positive regulation of tRNA methylation in response to nitrogen starvation