| Tag |
Content |
| dbPAF ID |
dbPAF-0016342 |
| Uniprot Accession |
Q10362; SET3_SCHPO; Q9USE1;
|
| Genbank Protein ID |
NP_594837.1;
|
| Genbank Nucleotide ID |
NM_001020266.2;
|
| Protein Name |
SET domain-containing protein 3 |
| Protein Synonyms/Alias |
|
| Gene Name |
set3 |
| Gene Synonyms/Alias |
SPAC22E12.11c; |
| Organism |
Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID |
284812 |
Functional Description
(View all) |
Transcriptional regulator that acts via the formation of large multiprotein complexes that modify and/or remodel the chromatin. Required for both gene activation and repression. Part of the Set3C complex, which is required to repress early/middle sporulation genes during meiosis. Required for the transcriptional activation of genes with high activity (By similarity).Functional Description
Transcriptional regulator that acts via the formation of large multiprotein complexes that modify and/or remodel the chromatin. Required for both gene activation and repression. Part of the Set3C complex, which is required to repress early/middle sporulation genes during meiosis. Required for the transcriptional activation of genes with high activity (By similarity). |
Phosphorylation Sites
|
dbPAF PTMs: 6 |
Sequence
(Fasta) | MWKIRCVCPF EDDDGFTIQC ESCEVWQHAV CVNIDANNVP EKYFCEQCQP RPIDADKAHK 60
IQLARLQREE EQSRILSRSR SSNNKRRTSF GKNGASPTHS ASPRQGNNTG ANGALFSQST 120
NSSNSGSYRN SVTGATLPNA HAPHSQNRRR RSNHLNNPPE APITEASNEY VYSFHLEYVP 180
LESNTFSASA LEYSKNLDLK NLDESEVLMD GCQVVPISSS KFCCSRFGLV STCEIPPNTP 240
IMEVKGRVCT QNEYKSDPKN QYNILGAPKP HVFFDSNSQL VVDSRVAGSK ARFARKGCQS 300
NSVVSSVYMN GSNSVPRFIL YSTTHIAPET EIIGDWTLDI SHPFRQFAPG MSRPSFNMEE 360
LELLSEVLST FLSFNECASQ DKKNCVFSRV TKYIKAARRA STANRVSVAK DRLSLTPSST 420
PSTPSPAESL PQPSNPTSVY AKSLKEFWLD KYRLSILQKW PAVKSLPTES VGIDVVMEPK 480
LQPSVKEKKP TKDLQSPLPS VEEDSSNRDK KTDIADLHTD SKVGIADVLS PISPDAALQS 540
DGPLKKAKEP EESSITPTTP PSFNVGESLS RRSASPLQHP RTSPDMLDKT SPCKRGLGTI 600
TTVHKKHGSV DHLPSVKRRR SIANDFHGKP DYNKRSLSIE RKPEAFKTKG DRPHKVHPSF 660
HRNSDSKLKL EPSSKEKSGS MFFNTLRTVK DKSHVHDTQR SSDVNFSRQN GTRSHSPSVS 720
PVGFSFDKSP VTTPPLPTAP APVITSRHAL VNNQFPTNNP NILDHKANNG DDISNALNTS 780
RSENKPNSNL VQGSVVKPSN TSASALPTSA PKKLSLSEYR QRRQQNILHQ QSKDNQAHGD 840
TARPHTVPAA TVSNPSFTR
Fasta Sequence
>Q10362|set3|Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
MWKIRCVCPFEDDDGFTIQCESCEVWQHAVCVNIDANNVPEKYFCEQCQPRPIDADKAHKIQLARLQREEEQSRILSRSRSSNNKRRTSFGKNGASPTHSASPRQGNNTGANGALFSQSTNSSNSGSYRNSVTGATLPNAHAPHSQNRRRRSNHLNNPPEAPITEASNEYVYSFHLEYVPLESNTFSASALEYSKNLDLKNLDESEVLMDGCQVVPISSSKFCCSRFGLVSTCEIPPNTPIMEVKGRVCTQNEYKSDPKNQYNILGAPKPHVFFDSNSQLVVDSRVAGSKARFARKGCQSNSVVSSVYMNGSNSVPRFILYSTTHIAPETEIIGDWTLDISHPFRQFAPGMSRPSFNMEELELLSEVLSTFLSFNECASQDKKNCVFSRVTKYIKAARRASTANRVSVAKDRLSLTPSSTPSTPSPAESLPQPSNPTSVYAKSLKEFWLDKYRLSILQKWPAVKSLPTESVGIDVVMEPKLQPSVKEKKPTKDLQSPLPSVEEDSSNRDKKTDIADLHTDSKVGIADVLSPISPDAALQSDGPLKKAKEPEESSITPTTPPSFNVGESLSRRSASPLQHPRTSPDMLDKTSPCKRGLGTITTVHKKHGSVDHLPSVKRRRSIANDFHGKPDYNKRSLSIERKPEAFKTKGDRPHKVHPSFHRNSDSKLKLEPSSKEKSGSMFFNTLRTVKDKSHVHDTQRSSDVNFSRQNGTRSHSPSVSPVGFSFDKSPVTTPPLPTAPAPVITSRHALVNNQFPTNNPNILDHKANNGDDISNALNTSRSENKPNSNLVQGSVVKPSNTSASALPTSAPKKLSLSEYRQRRQQNILHQQSKDNQAHGDTARPHTVPAATVSNPSFTR
|
| Keyword |
KW-0010--Activator
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0469--Meiosis
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
|
| Interpro |
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
|
| PROSITE |
PS50280--SET
PS01359--ZF_PHD_1
|
| Pfam |
PF00628--PHD
|
| Gene Ontology |
GO:0005634--C:nucleus
GO:0070210--C:Rpd3L-Expanded complex
GO:0034967--C:Set3 complex
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0070869--P:heterochromatin assembly involved in chromatin silencing
GO:0034968--P:histone lysine methylation
GO:0051321--P:meiotic cell cycle
GO:0006351--P:transcription, DNA-templated
|
