| Tag |
Content |
| dbPAF ID |
dbPAF-0016336 |
| Uniprot Accession |
Q10329; PSA4_SCHPO;
|
| Genbank Protein ID |
NP_595165.1;
|
| Genbank Nucleotide ID |
NM_001021074.2;
|
| Protein Name |
Probable proteasome subunit alpha type-4 |
| Protein Synonyms/Alias |
|
| Gene Name |
pre6 |
| Gene Synonyms/Alias |
SPBC106.16; |
| Organism |
Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID |
284812 |
Functional Description
(View all) |
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity).Functional Description
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity). |
Phosphorylation Sites
|
dbPAF PTMs: 1 | Position | Peptides | Source | References ( PMIDs ) |
|---|
| 12 | DRALSVFSPDGRLLQ | curated | 22817900 |
|
Sequence
(Fasta) | MSGYDRALSV FSPDGRLLQV EYGQEAVRRG TTAIALRGNE CIVIGVERKN VPKLQNVSNF 60
QKIAMVDNHV CLAFAGLNAD ARILIDKARV EAQNHKLNLA DPVSIEYLTR YVAGVQQKYT 120
QSGGVRPFGV STLIAGFDVG DNTPRVYQTE PAGIYNAWKA TAIGRASKAA REYLEKNWKE 180
GLSRDETIHL AVSSLLEVVQ TASGNIELAI MDPGKDVEFL HSDKIDTIVK EIQDEKEAEA 240
ARKKSGRSAP GVSTTSTIQ
Fasta Sequence
>Q10329|pre6|Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
MSGYDRALSVFSPDGRLLQVEYGQEAVRRGTTAIALRGNECIVIGVERKNVPKLQNVSNFQKIAMVDNHVCLAFAGLNADARILIDKARVEAQNHKLNLADPVSIEYLTRYVAGVQQKYTQSGGVRPFGVSTLIAGFDVGDNTPRVYQTEPAGIYNAWKATAIGRASKAAREYLEKNWKEGLSRDETIHLAVSSLLEVVQTASGNIELAIMDPGKDVEFLHSDKIDTIVKEIQDEKEAEAARKKSGRSAPGVSTTSTIQ
|
| Keyword |
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0378--Hydrolase
KW-0539--Nucleus
KW-0645--Protease
KW-0647--Proteasome
KW-1185--Reference proteome
KW-0888--Threonine protease
|
| Interpro |
IPR029055--Ntn_hydrolases_N
IPR000426--Proteasome_asu_N
IPR023332--Proteasome_suA-type
IPR001353--Proteasome_sua/b
|
| PROSITE |
PS00388--PROTEASOME_ALPHA_1
PS51475--PROTEASOME_ALPHA_2
|
| Pfam |
PF00227--Proteasome
PF10584--Proteasome_A_N
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0034399--C:nuclear periphery
GO:0005634--C:nucleus
GO:0005839--C:proteasome core complex
GO:0019773--C:proteasome core complex, alpha-subunit complex
GO:0004175--F:endopeptidase activity
GO:0004298--F:threonine-type endopeptidase activity
GO:0045842--P:positive regulation of mitotic metaphase/anaphase transition
GO:0010499--P:proteasomal ubiquitin-independent protein catabolic process
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
|
