dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0016333 |
| Uniprot Accession | Q10323; IMT3_SCHPO; Q9US96; |
| Genbank Protein ID | NP_593734.1; |
| Genbank Nucleotide ID | NM_001019165.2; |
| Protein Name | Inositol phosphoceramide mannosyltransferase 3 |
| Protein Synonyms/Alias | IPC mannosyltransferase 3; |
| Gene Name | SPAC17G8.11c |
| Gene Synonyms/Alias | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID | 284812 |
| Functional Description (View all) |
With imt1 and imt2, is required for the synthesis of mannosylinositol phosphoceramide (MIPC). Catalyzes the addition of mannosyl to inositol phosphoceramide (IPC). MIPC is essentiel for cell morphology, cell-surface distribution of ergosterol, localization for plasma-membrane transporters, and lipid-raft-mediated endocytosis of plasma membrane proteins to the vacuole. |
| Phosphorylation Sites |
dbPAF PTMs: 4 |
| Sequence (Fasta) | MNKILFYFFF FLTLILSATV YLFGGPMMLF FINYKTDLLK VDDVYNHEIY SNQSAAIPKI 60 IHQTWKTNEI PEKWVGAQKS CIDLHPDYEY VLWTDESMRE FIATDYPWFL TQYDSYPYNI 120 ERADVVRYFI LYKYGGIYLD LDVGCNRTLD PLLHYPAWVR RTSPSGISNN VMGFAKGHPF 180 LLQVVRNLPR FAFNYHFPYL TVMYSTGPLF LSIIWSAWRK LPDAEAWHHI WVMVPELYEK 240 SHHAFFEIYE GSSWHDSDAG FVFYMLHHWA IFTFLGFLTF FIVVYFIFGY ALKPAARVSR 300 TGRRVFSSPF SKTSPSRWKI FHRFTSSNEK YDQTRSDSLP FMSDYDLESQ TQSHSP 357 |
| Keyword | KW-0181--Complete proteome |
| Interpro | IPR007577--GlycoTrfase_DXD_sugar-bd_CS |
| PROSITE | |
| Pfam | PF04488--Gly_transf_sug |
| Gene Ontology | GO:0033106--C:cis-Golgi network membrane |