dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016328
Uniprot Accession Q10284; HSP75_SCHPO; O74730; P87181;
Genbank Protein ID NP_595438.1;
Genbank Nucleotide ID NM_001021346.2;
Protein Name Heat shock protein sks2
Protein Synonyms/Alias Heat shock cognate protein hsc1;
Gene Name sks2
Gene Synonyms/Alias hsc1;SPBC1709.05;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 May aid in the passage of the nascent polypeptide chain through the ribosome channel into the cytosol. Such an interaction could be crucial for continuous transport of the polypeptide; could serve to prevent the nascent polypeptide from interfering with translation by clogging the ribosome channel (By similarity).
Phosphorylation Sites
 dbPAF PTMs: 12
PositionPeptidesSourceReferences ( PMIDs )
40NDQGARTTPSFVAFTdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
151AVITVPAYFSDSQRAdbPTM 3.0;UniProt18257517; 16381945; 23193290
153ITVPAYFSDSQRAATdbPTM 3.0;UniProt18257517; 16381945; 23193290
155VPAYFSDSQRAATKDdbPTM 3.0;UniProt18257517; 16381945; 23193290
256RKQKIDISDDPRALRdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
353PKVQRLVSDFFDGRAdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
421GVVCPRNTPIPTIKKdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
501VEKTTGRSAHIEITNdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
509AHIEITNSVGHLSSTcurated22817900
514TNSVGHLSSTKIQEMdbPTM 3.0;UniProt18257517; 16381945; 23193290
515NSVGHLSSTKIQEMIdbPTM 3.0;UniProt18257517; 16381945; 23193290
516SVGHLSSTKIQEMIEdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
Sequence
(Fasta)		MSEVYEGAIG IDLGTTYSCV AVWETANVEI IPNDQGARTT PSFVAFTETE RLVGDAAKNQ 60
AAMNPRNTVF DAKRLIGRRY EDPETQKDIK HWPFKVIDNN GIPTIEVNYL GEKKQFTAQE 120
ISAMVLTKMK EISEAKLNKR VEKAVITVPA YFSDSQRAAT KDAGAIAGLN VLRIINEPTA 180
AAIAYGLDAK SDKPKNVLIF DLGGGTFDVS LLKIQGGVFE VLATAGDTHL GGEDFDNALV 240
EHFIQEFKRK QKIDISDDPR ALRRLRSACE RAKRALSSVT QTTVEVDSLS NGIDFSSSIT 300
RARFEDINAT TFKATIDPVA KVLKDSKVPK ADVHDIVLVG GSTRIPKVQR LVSDFFDGRA 360
LNKSINPDEA VAYGAAVQAA VLTNKADSDK TQDLLLLDVV PLSLGVAMEG NVFGVVCPRN 420
TPIPTIKKRT FTTVADNQTT VTFPVYQGER VNCAENEPLG EFQLTGIPPM PRGQAELEAT 480
FELDANGILK VTAVEKTTGR SAHIEITNSV GHLSSTKIQE MIENADKFKQ QDKDFAKKLE 540
AKSQLESYIS NIETTISEPN VMMKLKRGDK SKIEAQLAEC MSQLELEDTN TDALRKAELR 600
LKRTVQKAFA SLR 614
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0346--Stress response
Interpro

IPR018181--Heat_shock_70_CS
IPR029048--HSP70_C
IPR029047--HSP70_peptide-bd
IPR013126--Hsp_70_fam
PROSITE

PS00297--HSP70_1
PS00329--HSP70_2
PS01036--HSP70_3
Pfam

PF00012--HSP70
Gene Ontology

GO:0005829--C:cytosol
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0051082--F:unfolded protein binding
GO:0051083--P:'de novo' cotranslational protein folding
GO:0061077--P:chaperone-mediated protein folding
GO:0006364--P:rRNA processing
GO:0006412--P:translation