| Tag |
Content |
| dbPAF ID |
dbPAF-0006826 |
| Uniprot Accession |
P21283; VATC1_HUMAN;
|
| Genbank Protein ID |
NP_001686.1;
|
| Genbank Nucleotide ID |
NM_001695.4;
|
| Protein Name |
V-type proton ATPase subunit C 1 |
| Protein Synonyms/Alias |
|
| Gene Name |
ATP6V1C1 |
| Gene Synonyms/Alias |
ATP6C;ATP6D;VATC; |
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.Functional Description
Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. |
Phosphorylation Sites
|
dbPAF PTMs: 4 |
Sequence
(Fasta) | MTEFWLISAP GEKTCQQTWE KLHAATSKNN NLAVTSKFNI PDLKVGTLDV LVGLSDELAK 60
LDAFVEGVVK KVAQYMADVL EDSKDKVQEN LLANGVDLVT YITRFQWDMA KYPIKQSLKN 120
ISEIIAKGVT QIDNDLKSRA SAYNNLKGNL QNLERKNAGS LLTRSLAEIV KKDDFVLDSE 180
YLVTLLVVVP KLNHNDWIKQ YETLAEMVVP RSSNVLSEDQ DSYLCNVTLF RKAVDDFRHK 240
ARENKFIVRD FQYNEEEMKA DKEEMNRLST DKKKQFGPLV RWLKVNFSEA FIAWIHVKAL 300
RVFVESVLRY GLPVNFQAML LQPNKKTLKK LREVLHELYK HLDSSAAAII DAPMDIPGLN 360
LSQQEYYPYV YYKIDCNLLE FK
383Fasta Sequence
>P21283|ATP6V1C1|Homo sapiens(Human)
MTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGVVKKVAQYMADVLEDSKDKVQENLLANGVDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSEYLVTLLVVVPKLNHNDWIKQYETLAEMVVPRSSNVLSEDQDSYLCNVTLFRKAVDDFRHKARENKFIVRDFQYNEEEMKADKEEMNRLSTDKKKQFGPLVRWLKVNFSEAFIAWIHVKALRVFVESVLRYGLPVNFQAMLLQPNKKTLKKLREVLHELYKHLDSSAAAIIDAPMDIPGLNLSQQEYYPYVYYKIDCNLLEFK
|
| Keyword |
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0375--Hydrogen ion transport
KW-0406--Ion transport
KW-1185--Reference proteome
KW-0813--Transport
|
| Interpro |
IPR004907--ATPase_V1-cplx_csu
|
| PROSITE |
|
| Pfam |
PF03223--V-ATPase_C
|
| Gene Ontology |
GO:0045177--C:apical part of cell
GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005765--C:lysosomal membrane
GO:0005886--C:plasma membrane
GO:0016469--C:proton-transporting two-sector ATPase complex
GO:0033180--C:proton-transporting V-type ATPase, V1 domain
GO:0008553--F:hydrogen-exporting ATPase activity, phosphorylative mechanism
GO:0046961--F:proton-transporting ATPase activity, rotational mechanism
GO:0005215--F:transporter activity
GO:0015991--P:ATP hydrolysis coupled proton transport
GO:0006879--P:cellular iron ion homeostasis
GO:0008286--P:insulin receptor signaling pathway
GO:0034220--P:ion transmembrane transport
GO:0090382--P:phagosome maturation
GO:0015992--P:proton transport
GO:0033572--P:transferrin transport
GO:0055085--P:transmembrane transport
|
