dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0006796
Uniprot Accession P20941; PHOS_HUMAN; Q14816; Q9UP22; Q9UP23;
Genbank Protein ID NP_002588.3; NP_072098.1; XP_011507905.1;
Genbank Nucleotide ID NM_002597.4; NM_022576.3; XM_011509603.1;
Protein Name Phosducin
Protein Synonyms/Alias
Gene Name PDC
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. Inhibits the transcriptional activation activity of the cone-rod homeobox CRX.
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
36WRKFKLESQDSDSIPPhosphoSitePlus22135298
54KEILRQMSSPQSRNGdbPTM 3.0;HPRD 911331285; 16381945; 23193290; 18988627
73ERVSRKMSIQEYELIdbPTM 3.0;HPRD 92394752; 11331285; 16381945; 23193290; 18988627
Sequence
(Fasta)		MEEAKSQSLE EDFEGQATHT GPKGVINDWR KFKLESQDSD SIPPSKKEIL RQMSSPQSRN 60
GKDSKERVSR KMSIQEYELI HKEKEDENCL RKYRRQCMQD MHQKLSFGPR YGFVYELETG 120
KQFLETIEKE LKITTIVVHI YEDGIKGCDA LNSSLTCLAA EYPIVKFCKI KASNTGAGDR 180
FSLDVLPTLL IYKGGELISN FISVAEQFAE EFFAGDVESF LNEYGLLPER EVHVLEHTKI 240
EEEDVE 247
Keyword

KW-0025--Alternative splicing
KW-0966--Cell projection
KW-0969--Cilium
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0716--Sensory transduction
KW-0844--Vision
Interpro

IPR001200--Phosducin
IPR023196--Phosducin_N_dom
IPR024253--Phosducin_thioredoxin-like_dom
IPR012336--Thioredoxin-like_fold
PROSITE
Pfam

PF02114--Phosducin
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0001917--C:photoreceptor inner segment
GO:0001750--C:photoreceptor outer segment
GO:0004859--F:phospholipase inhibitor activity
GO:0007186--P:G-protein coupled receptor signaling pathway
GO:0043086--P:negative regulation of catalytic activity
GO:0007602--P:phototransduction
GO:0007601--P:visual perception